Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

BI‑3231

Catalog No. T73446Cas No. 2894848-07-6

BI‑3231 is a selective and potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.

BI‑3231

BI‑3231

Purity: 98.2%
Catalog No. T73446Cas No. 2894848-07-6
BI‑3231 is a selective and potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.
Pack SizePriceAvailabilityQuantity
1 mg$129In Stock
5 mg$322In Stock
10 mg$513In Stock
25 mg$987In Stock
50 mg$1,630In Stock
100 mg$2,630In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "BI‑3231"

Select Batch
Purity:98.2%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
BI‑3231 is a selective and potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.
In vitro
In vitro Pharmacology, B1-3231 demonstrates a good metabolic clearance rate.[1].
In vivo
Plasma and liver pharmacokinetics in mice after single oral administration of 50 μmol/kg 45 (BI-3231) showing extensive compound distribution and retention in the liver compared to plasmav[1].
Chemical Properties
Molecular Weight380.37
FormulaC16H14F2N4O3S
Cas No.2894848-07-6
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (262.90 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6290 mL13.1451 mL26.2902 mL131.4510 mL
5 mM0.5258 mL2.6290 mL5.2580 mL26.2902 mL
10 mM0.2629 mL1.3145 mL2.6290 mL13.1451 mL
20 mM0.1315 mL0.6573 mL1.3145 mL6.5725 mL
50 mM0.0526 mL0.2629 mL0.5258 mL2.6290 mL
100 mM0.0263 mL0.1315 mL0.2629 mL1.3145 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy BI‑3231 | purchase BI‑3231 | BI‑3231 cost | order BI‑3231 | BI‑3231 chemical structure | BI‑3231 in vivo | BI‑3231 in vitro | BI‑3231 formula | BI‑3231 molecular weight