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BI‑3231 is a selective and potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $129 | In Stock | |
5 mg | $322 | In Stock | |
10 mg | $513 | In Stock | |
25 mg | $987 | In Stock | |
50 mg | $1,630 | In Stock | |
100 mg | $2,630 | In Stock |
Description | BI‑3231 is a selective and potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis. |
In vitro | In vitro Pharmacology, B1-3231 demonstrates a good metabolic clearance rate.[1]. |
In vivo | Plasma and liver pharmacokinetics in mice after single oral administration of 50 μmol/kg 45 (BI-3231) showing extensive compound distribution and retention in the liver compared to plasmav[1]. |
Molecular Weight | 380.37 |
Formula | C16H14F2N4O3S |
Cas No. | 2894848-07-6 |
Smiles | O=C1C(=CN(C(=O)N1CC)CC2=NN=C(S2)C=3C=CC(F)=C(O)C3F)C |
Storage | store at low temperature,keep away from direct sunlight | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (262.90 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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