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BW 723C86

🥰Excellent
Catalog No. T21625Cas No. 160521-72-2
Alias BW723C86

BW 723C86 is a selective 5-HT2B receptor agonist with anxiolytic activity. It induces overeating and reduced grooming in rats and can be used in neurodegenerative disease research.

BW 723C86

BW 723C86

🥰Excellent
Catalog No. T21625Alias BW723C86Cas No. 160521-72-2
BW 723C86 is a selective 5-HT2B receptor agonist with anxiolytic activity. It induces overeating and reduced grooming in rats and can be used in neurodegenerative disease research.
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2 mg$52In Stock
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Product Introduction

Bioactivity
Description
BW 723C86 is a selective 5-HT2B receptor agonist with anxiolytic activity. It induces overeating and reduced grooming in rats and can be used in neurodegenerative disease research.
In vivo
Subcutaneous administration of 10 and 20 mg/kg BW 723C86 hydrochloride prolonged the duration of feeding behavior in ad libitum-fed rats over a 15-minute period in the observation cage. By systemic administration (subcutaneous injection of 1, 10, and 20 mg/kg, 30 minutes prior to testing), but not intracerebroventricular administration (1-30 μg), BW 723C86 hydrochloride similarly significantly reduced the frequency of grooming behavior in rats in the observation cage. [1]
AliasBW723C86
Chemical Properties
Molecular Weight322.85
FormulaC16H19ClN2OS
Cas No.160521-72-2
SmilesCl.O(C=1C=CC=2NC=C(C2C1)CC(N)C)CC=3SC=CC3
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (247.79 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0974 mL15.4871 mL30.9741 mL154.8707 mL
5 mM0.6195 mL3.0974 mL6.1948 mL30.9741 mL
10 mM0.3097 mL1.5487 mL3.0974 mL15.4871 mL
20 mM0.1549 mL0.7744 mL1.5487 mL7.7435 mL
50 mM0.0619 mL0.3097 mL0.6195 mL3.0974 mL
100 mM0.0310 mL0.1549 mL0.3097 mL1.5487 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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