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Ceftobiprole medocaril (BAL5788), the parenteral prodrug of Ceftobiprole, is a broad-spectrum cephalosporin effective against Methicillin-resistant Staphylococcus aureus (MRSA).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $195 | In Stock | |
5 mg | $437 | In Stock | |
10 mg | $646 | In Stock | |
25 mg | $987 | In Stock | |
50 mg | $1,380 | In Stock |
Description | Ceftobiprole medocaril (BAL5788), the parenteral prodrug of Ceftobiprole, is a broad-spectrum cephalosporin effective against Methicillin-resistant Staphylococcus aureus (MRSA). |
In vivo | Ceftobiprole medocaril (10, 40, 160 mg/kg; single dose; sc) has T 1/2 s from 20 min to 31 min, as the dose rose from 40 mg/kg to 160 mg/kg. The AUC/dose values for the escalating single doses ranges from 0.585 to 1.33, and the C max /dose values decreases from 1.08 to 0.90 in neutropenic thigh-infected mice [1]. The drug showed activities in the lung model similar to those in the thigh model. |
Alias | BAL5788 |
Molecular Weight | 690.66 |
Formula | C26H26N8O11S2 |
Cas No. | 376653-43-9 |
Smiles | C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\O)/C=3N=C(N)SN3)=O)C2=O)(SCC1/C=C\4/C(=O)N(CC4)[C@H]5CN(C(OCC=6OC(=O)OC6C)=O)CC5)[H] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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