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Cephalothin sodium

Cephalothin sodium
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Purity:99.17%
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Cephalothin sodium

Catalog No. T1122Cas No. 58-71-9
Cephalothin sodium (Cefalotin) binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cephalothin sodium (Cefalotin) is the sodium salt form of cephalothin, a semisynthetic, beta-lactam, the first-generation cephalosporin antibiotic with bactericidal activity. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
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100 mg$50In Stock
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Product Introduction

Bioactivity
Description
Cephalothin sodium (Cefalotin) binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cephalothin sodium (Cefalotin) is the sodium salt form of cephalothin, a semisynthetic, beta-lactam, the first-generation cephalosporin antibiotic with bactericidal activity. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
AliasCefalotin sodium, Cephalothin, Cefalotin
Chemical Properties
Molecular Weight418.4
FormulaC16H15N2NaO6S2
Cas No.58-71-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 119.5mM
DMSO: 50 mg/mL (119.5 mM)
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.3901 mL11.9503 mL23.9006 mL119.5029 mL
5 mM0.4780 mL2.3901 mL4.7801 mL23.9006 mL
10 mM0.2390 mL1.1950 mL2.3901 mL11.9503 mL
20 mM0.1195 mL0.5975 mL1.1950 mL5.9751 mL
50 mM0.0478 mL0.2390 mL0.4780 mL2.3901 mL
100 mM0.0239 mL0.1195 mL0.2390 mL1.1950 mL

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