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CNQX disodium

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Catalog No. T8458Cas No. 479347-85-8

CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.

CNQX disodium

CNQX disodium

🥰Excellent
Purity: 97.77%
Catalog No. T8458Cas No. 479347-85-8
CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.
Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$55In Stock
25 mg$122In Stock
50 mg$197In Stock
100 mg$313In Stock
200 mg$463In Stock
500 mg$753In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Purity:97.77%
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Product Introduction

Bioactivity
Description
CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.
Targets&IC50
AMPA:0.3 μM (IC50), Kainate receptor:1.5 μM (IC50)
In vivo
The ED50 for ?CNQX was 45.9+/-4.65 microg, respectively.?Intrathecal injection of a combination of CNQX and gabapentin produced a strong synergistic antiallodynic effect in neuropathic rats[1].
Chemical Properties
Molecular Weight276.12
FormulaC9H2N4Na2O4
Cas No.479347-85-8
Smiles[Na+].[Na+].[O-]c1nc2cc(C#N)c(cc2nc1[O-])[N+]([O-])=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (90.54 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6216 mL18.1081 mL36.2161 mL181.0807 mL
5 mM0.7243 mL3.6216 mL7.2432 mL36.2161 mL
10 mM0.3622 mL1.8108 mL3.6216 mL18.1081 mL
20 mM0.1811 mL0.9054 mL1.8108 mL9.0540 mL
50 mM0.0724 mL0.3622 mL0.7243 mL3.6216 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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