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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $97 | In Stock | |
5 mg | $277 | In Stock | |
10 mg | $437 | In Stock | |
25 mg | $713 | In Stock | |
50 mg | $985 | In Stock | |
100 mg | $1,320 | In Stock | |
500 mg | $2,660 | In Stock | |
1 mL x 10 mM (in DMSO) | $353 | In Stock |
Description | 1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardial I/R and protect the liver from CCl4-induced acute hepatotoxicity, by reducing oxidative stress and suppressing inflammatory responses. 4. Cornuside has anti-inflammatory activity by downregulations of iNOS and COX-2 due to NF-κB inhibition as well as the negative regulation of ERK1/2, p38, and JNK1/2 phosphorylations in RAW 264.7 cells. 5. Cornuside has protective potential against cerebral ischemic injury, may be due to the suppression of intracellular Ca(2+) elevation and caspase-3 activity, and improvements in mitochondrial energy metabolism and antioxidant properties. |
Alias | 7-Galloylsecologanol, 7-O-Galloylsecologanol, Comuside |
Molecular Weight | 542.49 |
Formula | C24H30O14 |
Cas No. | 131189-57-6 |
Storage | keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 65 mg/mL (119.82 mM) ![]() Pyridine, Methanol, etc.: Soluble Ethanol: Soluble | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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