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Cosalane

TargetMol
Cosalane
Cosalane (NSC 658586) is an HIV replication inhibitor, an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice, with antiviral activity that blocks the binding of CCR7 to its natural ligands, CCL19 and CCL21.
Catalog No. T23910Cas No. 154212-56-3
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Purity:100%
ee:99.84%
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Cosalane

TargetMol
Catalog No. T23910Cas No. 154212-56-3
Cosalane (NSC 658586) is an HIV replication inhibitor, an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice, with antiviral activity that blocks the binding of CCR7 to its natural ligands, CCL19 and CCL21.
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Pack SizePriceAvailabilityQuantity
1 mg$462In Stock
5 mg$1,070In Stock
10 mg$1,320In Stock
25 mg$1,750In Stock
50 mg$2,180In Stock
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Product Introduction

Bioactivity
Description
Cosalane (NSC 658586) is an HIV replication inhibitor, an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice, with antiviral activity that blocks the binding of CCR7 to its natural ligands, CCL19 and CCL21.
AliasNSC 658586, NSC-658586, NSC 640067
Chemical Properties
Molecular Weight767.86
FormulaC45H60Cl2O6
Cas No.154212-56-3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (130.23 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3023 mL6.5116 mL13.0232 mL65.1160 mL
5 mM0.2605 mL1.3023 mL2.6046 mL13.0232 mL
10 mM0.1302 mL0.6512 mL1.3023 mL6.5116 mL
20 mM0.0651 mL0.3256 mL0.6512 mL3.2558 mL
50 mM0.0260 mL0.1302 mL0.2605 mL1.3023 mL
100 mM0.0130 mL0.0651 mL0.1302 mL0.6512 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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