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CU-CPT17e
🥰Excellent
Catalog No. T10899Cas No. 2109805-75-4
CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).
CU-CPT17e
🥰Excellent
Purity: 98.49%
Catalog No. T10899Cas No. 2109805-75-4
CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $213 | In Stock | |
| 5 mg | $441 | In Stock | |
| 10 mg | $649 | In Stock | |
| 25 mg | $987 | In Stock | |
| 50 mg | $1,390 | In Stock | |
| 100 mg | $1,870 | In Stock |
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Purity:98.49%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9). |
| In vitro | The first small molecule 17e (CU-CPT17e) capable of simultaneously activating TLRs 3, 8, and 9. Biochemical studies demonstrated that 17e could induce a strong immune response via the production of various cytokines in human monocytic THP-1 cells. Furthermore, 17e inhibited the proliferation of HeLa cancer cells by triggering apoptosis and arresting the cell cycle at the S phase. These results showcase potential therapeutic applications of 17e in both vaccine adjuvants and anticancer therapies based on multi-TLR activation. |
| Molecular Weight | 504.49 |
| Formula | C27H24N2O8 |
| Cas No. | 2109805-75-4 |
| Smiles | [O-][N+](=O)c1ccc(COc2cc3OC4(CCOCC4)C=Cc3cc2OCc2ccc(cc2)[N+]([O-])=O)cc1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | DMSO: 2 mg/mL (3.96 mM), Sonication is recommended.  | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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