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D-ERYTHRO-SPHINGOSINE

Catalog No. T5891Cas No. 123-78-4
Alias trans-4-Sphingenine, Erythrosphingosine, erythro-C18-Sphingosine

D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator

D-ERYTHRO-SPHINGOSINE

D-ERYTHRO-SPHINGOSINE

Purity: 98.00%
Catalog No. T5891Alias trans-4-Sphingenine, Erythrosphingosine, erythro-C18-SphingosineCas No. 123-78-4
D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator
Pack SizePriceAvailabilityQuantity
10 mg$39In Stock
25 mg$64In Stock
50 mg$113In Stock
100 mg$172In Stock
500 mg$428In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Purity:98.00%
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Product Introduction

Bioactivity
Description
D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator
Targets&IC50
p32:8 μM (EC50)
In vitro
D-erythro-Sphingosine inhibits protein kinase C in vitro[1]. D-erythro-Sphingosine has been shown to inhibit protein kinase C, which affects cell regulation and several signal transduction pathways, and exhibits antitumor promoter activities in various mammalian cells[2].
Aliastrans-4-Sphingenine, Erythrosphingosine, erythro-C18-Sphingosine
Chemical Properties
Molecular Weight299.49
FormulaC18H37NO2
Cas No.123-78-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 250 mg/mL (834.75 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3390 mL16.6950 mL33.3901 mL166.9505 mL
5 mM0.6678 mL3.3390 mL6.6780 mL33.3901 mL
10 mM0.3339 mL1.6695 mL3.3390 mL16.6950 mL
20 mM0.1670 mL0.8348 mL1.6695 mL8.3475 mL
50 mM0.0668 mL0.3339 mL0.6678 mL3.3390 mL
100 mM0.0334 mL0.1670 mL0.3339 mL1.6695 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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