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D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $39 | In Stock | |
25 mg | $64 | In Stock | |
50 mg | $113 | In Stock | |
100 mg | $172 | In Stock | |
500 mg | $428 | In Stock | |
1 mL x 10 mM (in DMSO) | $43 | In Stock |
Description | D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator |
Targets&IC50 | p32:8 μM (EC50) |
In vitro | D-erythro-Sphingosine inhibits protein kinase C in vitro[1]. D-erythro-Sphingosine has been shown to inhibit protein kinase C, which affects cell regulation and several signal transduction pathways, and exhibits antitumor promoter activities in various mammalian cells[2]. |
Alias | trans-4-Sphingenine, Erythrosphingosine, erythro-C18-Sphingosine |
Molecular Weight | 299.49 |
Formula | C18H37NO2 |
Cas No. | 123-78-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 250 mg/mL (834.75 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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