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D-glutamine

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Catalog No. T6468Cas No. 5959-95-5

D-Glutamine is the D-type stereoisomer of cell-permeable glutamine, one of the 20 amino acids encoded by the standardized genetic code.

D-glutamine

D-glutamine

🥰Excellent
Purity: 99.92%
Catalog No. T6468Cas No. 5959-95-5
D-Glutamine is the D-type stereoisomer of cell-permeable glutamine, one of the 20 amino acids encoded by the standardized genetic code.
Pack SizePriceAvailabilityQuantity
25 mg$30In Stock
50 mg$46In Stock
100 mg$60In Stock
200 mg$90In Stock
500 mg$148In Stock
1 mL x 10 mM (in H2O)$39In Stock
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Purity:99.92%
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Product Introduction

Bioactivity
Description
D-Glutamine is the D-type stereoisomer of cell-permeable glutamine, one of the 20 amino acids encoded by the standardized genetic code.
In vitro
In catabolic states of injury and illness, glutamine becomes conditionally-essential (requiring intake from food or supplements). Glutamine is the most abundant naturally occurring, non-essential amino acid in the human body and one of the few amino acids that can directly cross the blood–brain barrier. [1] Glutamine is a key pharmaconutrient in the body's response to stress and injury. Glutamine exerts its protective effects via multiple mechanisms, including direct protection of cells and tissue from injury, attenuation inflammation, and preservation of metabolic function. [1]
In vivo
Glutamine shows the greatest benefit when administered at doses greater than 0.35 g/kg/day, with optimal benefit potentially occurring at 0.5 g/kg/day. [2]
Cell Research
Effect of D-Glutamine and glutaminase inhibitor on acetaldehyde-induced permeability. Caco-2 cell monolayers are incubated for 4 h without or with acetaldehyde (600 μM) and L-Glutamine or D-Glutamine (2 mM) in the absence or presence of 6-diazo-5-oxo-L-norleucine (DON). Transepithelial electrical resistance (TER) and FITC-inulin flux are measured. Values are means±SE (n=6)[2].
Chemical Properties
Molecular Weight146.14
FormulaC5H10N2O3
Cas No.5959-95-5
Smiles[H][C@@](N)(CCC(N)=O)C(O)=O
Relative Density.1.321 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: Insoluble
H2O: 10 mM
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM6.8428 mL34.2138 mL68.4275 mL342.1377 mL
5 mM1.3686 mL6.8428 mL13.6855 mL68.4275 mL
10 mM0.6843 mL3.4214 mL6.8428 mL34.2138 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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