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Dazoxiben

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Catalog No. T7968Cas No. 74226-22-5
Alias UK-37248

Dazoxiben (UK-37248) is a potent inhibitor of thromboxane (TX) synthase

Dazoxiben

Dazoxiben

🥰Excellent
Purity: 99.99%
Catalog No. T7968Alias UK-37248Cas No. 74226-22-5
Dazoxiben (UK-37248) is a potent inhibitor of thromboxane (TX) synthase
Pack SizePriceAvailabilityQuantity
1 mg$32In Stock
2 mg$45In Stock
5 mg$73In Stock
10 mg$129In Stock
25 mg$263In Stock
50 mg$388In Stock
100 mg$538In Stock
500 mg$1,150In Stock
1 mL x 10 mM (in DMSO)$54In Stock
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Purity:99.99%
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Product Introduction

Bioactivity
Description
Dazoxiben (UK-37248) is a potent inhibitor of thromboxane (TX) synthase
In vitro
Dazoxiben, an orally active TX-synthase inhibitor, on platelet and renal TXB2 production and associated changes in PG-endoperoxide metabolism. Dazoxiben inhibits TXB2 production in clotting human whole blood with an IC50 of 0.3 micrograms/ml and causes parallel enhancement of PGE2 greater than PGF2 alpha greater than 6-keto-PGF1 alpha production[1].
AliasUK-37248
Chemical Properties
Molecular Weight268.7
FormulaC12H13ClN2O3
Cas No.74226-22-5
SmilesCl.OC(=O)c1ccc(OCCn2ccnc2)cc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 62.5 mg/mL (232.60 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7216 mL18.6081 mL37.2162 mL186.0811 mL
5 mM0.7443 mL3.7216 mL7.4432 mL37.2162 mL
10 mM0.3722 mL1.8608 mL3.7216 mL18.6081 mL
20 mM0.1861 mL0.9304 mL1.8608 mL9.3041 mL
50 mM0.0744 mL0.3722 mL0.7443 mL3.7216 mL
100 mM0.0372 mL0.1861 mL0.3722 mL1.8608 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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