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E-3620

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Catalog No. T62107Cas No. 151213-86-4

E-3620 is a novel 5-HT3 receptor antagonist that inhibits cisplatin-induced vomiting in beagles. E-3620 can be used to study dyskinesia, gastrointestinal dyskinesia, psoriasis and psoriasis.

E-3620

E-3620

😃Good
Purity: 98.88%
Catalog No. T62107Cas No. 151213-86-4
E-3620 is a novel 5-HT3 receptor antagonist that inhibits cisplatin-induced vomiting in beagles. E-3620 can be used to study dyskinesia, gastrointestinal dyskinesia, psoriasis and psoriasis.
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1 mg$196In Stock
5 mgInquiry6-8 weeks
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Purity:98.88%
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Product Introduction

Bioactivity
Description
E-3620 is a novel 5-HT3 receptor antagonist that inhibits cisplatin-induced vomiting in beagles. E-3620 can be used to study dyskinesia, gastrointestinal dyskinesia, psoriasis and psoriasis.
Chemical Properties
Molecular Weight412.35
FormulaC20H27Cl2N3O2
Cas No.151213-86-4
SmilesCl.CC#C[C@H](C)Oc1cc(N)c(Cl)cc1C(=O)N[C@@H]1C[C@@H]2CC[C@H](C1)N2C
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (194.01 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4251 mL12.1256 mL24.2512 mL121.2562 mL
5 mM0.4850 mL2.4251 mL4.8502 mL24.2512 mL
10 mM0.2425 mL1.2126 mL2.4251 mL12.1256 mL
20 mM0.1213 mL0.6063 mL1.2126 mL6.0628 mL
50 mM0.0485 mL0.2425 mL0.4850 mL2.4251 mL
100 mM0.0243 mL0.1213 mL0.2425 mL1.2126 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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