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EBV lytic cycle inducer-1 is an iron chelate analogue that induces the lytic cycle of EBV.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $83 | In Stock | |
5 mg | $196 | In Stock | |
10 mg | $297 | In Stock | |
25 mg | $519 | In Stock | |
50 mg | $733 | In Stock | |
100 mg | $987 | In Stock | |
500 mg | $1,980 | In Stock |
Description | EBV lytic cycle inducer-1 is an iron chelate analogue that induces the lytic cycle of EBV. |
In vitro | Dp44mT (EBV lytic cycle inducer-1)(compound C7) induces the lytic cycle in a cell-line-dependent manner, with a higher inductive capacity on AGS-BX1 cells compared to AGX cells, in the concentration range of 0-80 μM for 48 hours[1]. At 10 μM, Dp44mT(EBV lytic cycle inducer-1) induces the lytic cycle in a time-dependent manner over 0-72 hours[1]. At concentrations of 1.25-2.5 μM for 24 hours, Dp44mT(EBV lytic cycle inducer-1) synergistically induces the Epstein-Barr virus (EBV) lytic cycle with the HDAC inhibitors Romidespin and SAHA[1]. At 20 μM for 48 hours, Dp44mT(EBV lytic cycle inducer-1) reactivates the EBV lytic cycle by inducing the ERK-autophagy axis[2]. |
Alias | Dp44mT |
Molecular Weight | 318.17 |
Formula | C14H12BrN3O |
Cas No. | 394668-43-0 |
Smiles | O=C(NN=C(C1=NC=CC=C1)C)C=2C=CC=C(Br)C2 |
Relative Density. | 1.41 g/cm3 at 20℃ (Predicted) |
Storage | Shipping with blue ice. |
Solubility Information | DMSO: 1 mg/mL, Sonication is recommended. |
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