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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | $948 | In Stock |
Description | EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity. |
Targets&IC50 | EGFR (L858R/T790M):28 nM, EGFR (WT):7 nM |
In vitro | EGFR-IN-9 shows antiproliferative activity in HCC827 lung cancer cell line with an IC50 of 8 nM[1]. |
Molecular Weight | 476.53 |
Formula | C29H24N4O3 |
Cas No. | 1226549-39-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 90 mg/mL (188.9 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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