Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $89 | In Stock | |
5 mg | $228 | In Stock | |
10 mg | $368 | In Stock | |
25 mg | $573 | In Stock | |
50 mg | $778 | In Stock | |
100 mg | $1,160 | In Stock | |
1 mL x 10 mM (in DMSO) | $193 | In Stock |
Description | EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer. |
Targets&IC50 | CWR22:24 nM, DLKPA:16.3 nM, DU145 cells:40.3 nM, 22Rv1:21.7 nM, PC3:37.0 nM, DLKP:14.4 nM |
In vitro | In CWR22, 22Rv1, DU145, PC-3, DLKP, and doxorubicin-selected variant DLKPA cell lines, EL-102 (0-120 nM; 72 hours) inhibited cell proliferation with IC50 values of 24, 21.7, 40.3, 37.0, 14.4, and 16.3 nM, respectively[1]. |
In vivo | In nude mice bearing CWR22 xenografts, EL-102 (oral gavage; 12 and 15 mg/kg; administered every 5 days with 2 days off) showed no effect on tumor growth but enhanced the effect of docetaxel on the tumor[1]. |
Alias | EL102 |
Molecular Weight | 384.47 |
Formula | C19H16N2O3S2 |
Cas No. | 1233948-61-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 20 mg/mL (52.02 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.