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Enerisant HCl
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Enerisant HCl
Catalog No. T70489Cas No. 1152749-07-9
Enerisant HCl is a novel potent and selective histamine H3 receptor antagonist, a substrate for P-gp, mediated by cytochrome P450 (CYP) and transporter proteins.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 5 mg | $430 | In Stock | |
| 10 mg | $636 | In Stock | |
| 25 mg | $987 | In Stock | |
| 50 mg | $1,360 | In Stock | |
| 100 mg | $1,830 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Enerisant HCl is a novel potent and selective histamine H3 receptor antagonist, a substrate for P-gp, mediated by cytochrome P450 (CYP) and transporter proteins. |
| In vivo | Enerisant HCl (0.3-1 mg/kg; p.o.; once; Male SD rats) attenuates the biphagous response in rats.[1] Enerisant hydrochloride (0.1-3 mg/kg; p.o.; once; Male SD rats) causes histamine H3 receptor occupancy in a dose-dependent manner in rats. The dose causing half-maximal receptor occupancy was 0.78 mg/kg.[1] Enerisant HCl (1 mg/kg; s.c.; once; Male SD rats) increases total extracellular histamine levels in the posterior hypothalamus of rats.[1] Enerisant HCl (1 mg/kg; i.p.; once; Male SD rats) increases total extracellular dopamine and acetylcholine levels in the rat medial prefrontal cortex (mPFC).[1] |
| Molecular Weight | 434.96 |
| Formula | C22H31ClN4O3 |
| Cas No. | 1152749-07-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (114.95 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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