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FGFR4-IN-1

🥰Excellent
Catalog No. TQ0256Cas No. 1708971-72-5

FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).

FGFR4-IN-1

FGFR4-IN-1

🥰Excellent
Purity: 98.96%
Catalog No. TQ0256Cas No. 1708971-72-5
FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).
Pack SizePriceAvailabilityQuantity
1 mg$44In Stock
5 mg$97In Stock
10 mg$156In Stock
25 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$97In Stock
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Purity:98.96%
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Product Introduction

Bioactivity
Description
FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).
Targets&IC50
FGFR4:0.7 nM
In vitro
FGFR4-IN-1 inhibits the proliferation of hepatocellular carcinoma cells HuH-7 (IC50: 7.8 nM).
Chemical Properties
Molecular Weight493.52
FormulaC24H27N7O5
Cas No.1708971-72-5
SmilesCOCCNc1cc(NC(=O)N2CCCc3cc(CN4CCOCC4=O)c(C=O)nc23)ncc1C#N
Relative Density.1.41 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 6 mg/mL (12.16 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0263 mL10.1313 mL20.2626 mL101.3130 mL
5 mM0.4053 mL2.0263 mL4.0525 mL20.2626 mL
10 mM0.2026 mL1.0131 mL2.0263 mL10.1313 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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