Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GW590735 is an effective and selective PPARα agonist with an EC50 of 4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW590735 can be used in dyslipidemia studies.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 87.00 | |
5 mg | In stock | $ 213.00 | |
10 mg | In stock | $ 313.00 | |
25 mg | In stock | $ 533.00 | |
50 mg | In stock | $ 768.00 | |
100 mg | In stock | $ 1,080.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 225.00 |
Description | GW590735 is an effective and selective PPARα agonist with an EC50 of 4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW590735 can be used in dyslipidemia studies. |
In vivo | GW590735 (2 mg/kg; i.v.) shows Cl, Vd, T1/2, and F% are 13 mL/min/kg, 2.8 L/kg, 2.6 hours and 85%, respectively in dogs while GW590735 (2.7 mg/kg; i.v.) shows Cl, Vd, T1/2, and F% are 5 mL/min/kg, 1 L/kg, 2.4 hours and 47%, respectively in rats. In male C |
Molecular Weight | 478.48 |
Formula | C23H21F3N2O4S |
CAS No. | 343321-96-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (104.5 mM)
You can also refer to dose conversion for different animals. More
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GW590735 343321-96-0 DNA Damage/DNA Repair Metabolism PPAR lipid LDLc HDLc Peroxisome proliferator-activated receptors imbalance GW 590735 GW-590735 Inhibitor inhibit triglycerides dyslipidemia inhibitor