Shopping Cart
- Remove All
Your shopping cart is currently empty
H2L 5765834
🥰Excellent
Catalog No. T22834Cas No. 420841-84-5
H2L 5765834 is a lysophosphatidic acid receptors antagonist
H2L 5765834
🥰Excellent
Purity: 99.47%
Catalog No. T22834Cas No. 420841-84-5
H2L 5765834 is a lysophosphatidic acid receptors antagonist
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $56 | In Stock | |
| 5 mg | $122 | In Stock | |
| 10 mg | $197 | In Stock | |
| 25 mg | $372 | In Stock | |
| 50 mg | $553 | In Stock | |
| 100 mg | $787 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $133 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "H2L 5765834"
Fingolimod hydrochloride
Cited
FTY720 HCl, Fingolimod (FTY720) HCl
T2539162359-56-0
Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).
- $35
Size
QTY
CitedSiponimod Cited
BAF-312
T64031230487-00-9
BAF312 (Siponimod (BAF-312)), a next-generation S1P receptor modulator, is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibits >1000-fold over S1P2, S1P3 and S1P4 receptors.
- $33
Size
QTY
CitedKi16198
T6347355025-13-7
Ki16198 is an orally available LPA receptor antagonist and is a methyl ester derivative of Ki16425. It inhibits LPA1- and LPA3-induced inositol phosphates with Ki values of 0.34 and 0.93 μM, respectively, and can be used in studies of pancreatic carcinogenesis and metastasis.
- $30
Size
QTY
Tetradecyl Phosphonate
T76894671-75-4
Tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (LPA1), LPA2, and LPA3 receptors.
- $50
Size
QTY
Ozanimod
RPC-1063
T69231306760-87-1
Ozanimod (RPC-1063) (RPC1063) is a specific oral S1P Receptor 1 modulator. Ozanimod has been used in trials studying the treatment of Crohn's Disease, Ulcerative Colitis, Multiple Sclerosis, and Relapsing Multiple Sclerosis.
- $41
Size
QTY
Fingolimod Cited
FTY-720A, FTY-720
T7939162359-55-9
Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).
- $50
Size
QTY
CitedS1PR1 modulator 1
T128212328109-05-1In house
S1PR1 modulator 1 is a selective inhibitor of S1PR1, with a pIC50 of 7.6.
- $59
Size
QTY
ASP-4058
T10385952565-91-2In house
ASP-4058 is a selective, safe, and orally active second-generation agonist of sphingosine phosphate receptors 1 and 5 (S1P1 and S1P5).ASP-4058 ameliorates experimental autoimmune encephalomyelitis in mice.
- $100
Size
QTY
SLP9101555
T63047In house
SLP9101555 is a potent and selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of 90 nM.SLP9101555 has a high affinity for SphK2, which is 200-fold higher than that of SphK1.SLP9101555 dramatically reduces extracellular S1P sphingosine 1-phosphate (S1P) levels.
- $350
Size
QTY
Radioprotectin-1
5-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl]benzoic acid
T126841622006-09-0In house
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.
- $74
Size
QTY
CYM50260
T150311355026-60-6In house
CYM50260 is a potent and highly selective agonist of the sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM), exhibiting no activity against S1P1-R, S1P2-R, S1P3-R, and S1P5-R.
- $48
Size
QTY
UCM-05194
UCM05194, UCM 05194
T696472411412-36-5In house
UCM-05194 is a selective LPA1 receptor agonist that can improve neuropathic pain and can be used in the study of progressive system diseases.
- $333
Size
QTY
Select Batch
Purity:99.47%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | H2L 5765834 is a lysophosphatidic acid receptors antagonist |
| Targets&IC50 | LPA3 receptor:752 nM (IC50), LPA5 receptor:463 nM (IC50), LPA1 receptor:94 nM (IC50) |
| Molecular Weight | 404.33 |
| Formula | C21H12N2O7 |
| Cas No. | 420841-84-5 |
| Smiles | OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1cccc(Oc2ccc(cc2)[N+]([O-])=O)c1 |
| Relative Density. | 1.544 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (136.03 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy H2L 5765834 | purchase H2L 5765834 | H2L 5765834 cost | order H2L 5765834 | H2L 5765834 chemical structure | H2L 5765834 formula | H2L 5765834 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.