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Isobarbaloin

🥰Excellent
Catalog No. T0176Cas No. 5133-19-7
Alias Barbaloin-A, Aloin-A, Aloin

Isobarbaloin (Barbaloin-A) (Aloin) is a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.

Isobarbaloin

Isobarbaloin

🥰Excellent
Purity: 100%
Catalog No. T0176Alias Barbaloin-A, Aloin-A, AloinCas No. 5133-19-7
Isobarbaloin (Barbaloin-A) (Aloin) is a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
Pack SizePriceAvailabilityQuantity
10 mg$30In Stock
25 mg$38In Stock
50 mg$58In Stock
100 mg$92In Stock
500 mg$218In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Isobarbaloin (Barbaloin-A) (Aloin) is a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
In vivo
In the MCF-7 cell line, Aloin diminishes the proportion of cells in mitosis by inducing apoptosis, suppresses the expression of topoisomerase IIα, and downregulates cyclin B1 protein expression. In HeLaS3 cells, Aloin exhibits significant antiproliferative effects at physiological concentration (IC50=97 μM), leading to cell cycle arrest in the S phase and a marked increase in apoptosis.
AliasBarbaloin-A, Aloin-A, Aloin
Chemical Properties
Molecular Weight418.39
FormulaC21H22O9
Cas No.5133-19-7
SmilesO=C1C2=C(C=CC=C2O)[C@H]([C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C4=CC(CO)=CC(O)=C14
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 83 mg/mL (198.37 mM)
H2O: 1 mg/mL (2.39 mM)
Ethanol: 2 mg/mL (4.78 mM)
Solution Preparation Table
H2O/Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.3901 mL11.9506 mL23.9011 mL119.5057 mL

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