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Isobarbaloin
Catalog No. T0176Cas No. 5133-19-7
Alias Barbaloin-A, Aloin-A, Aloin
Isobarbaloin (Barbaloin-A) (Aloin) is a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
Isobarbaloin
Catalog No. T0176Alias Barbaloin-A, Aloin-A, AloinCas No. 5133-19-7
Isobarbaloin (Barbaloin-A) (Aloin) is a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $50 | In Stock | |
| 25 mg | $64 | In Stock | |
| 50 mg | $97 | In Stock | |
| 100 mg | $153 | In Stock | |
| 200 mg | $218 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Isobarbaloin (Barbaloin-A) (Aloin) is a natural anthracycline from Aloe vera, is a tyrosinase inhibitor. |
| In vivo | In the MCF-7 cell line, Aloin diminishes the proportion of cells in mitosis by inducing apoptosis, suppresses the expression of topoisomerase IIα, and downregulates cyclin B1 protein expression. In HeLaS3 cells, Aloin exhibits significant antiproliferative effects at physiological concentration (IC50=97 μM), leading to cell cycle arrest in the S phase and a marked increase in apoptosis. |
| Alias | Barbaloin-A, Aloin-A, Aloin |
| Molecular Weight | 418.39 |
| Formula | C21H22O9 |
| Cas No. | 5133-19-7 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | DMSO: 83 mg/mL (198.37 mM) H2O: 1 mg/mL (2.39 mM) Ethanol: 2 mg/mL (4.78 mM) | ||||||||||
Solution Preparation Table | |||||||||||
H2O/Ethanol/DMSO
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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