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KRAS inhibitor-9

Catalog No. T8756Cas No. 300809-71-6
Alias DUN09716

KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSC-LC cells with KRAS mutation but not normal lung cells

KRAS inhibitor-9

KRAS inhibitor-9

Purity: 99.94%
Catalog No. T8756Alias DUN09716Cas No. 300809-71-6
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSC-LC cells with KRAS mutation but not normal lung cells
Pack SizePriceAvailabilityQuantity
1 mg$33In Stock
5 mg$73In Stock
10 mg$119In Stock
25 mg$223In Stock
50 mg$323In Stock
100 mg$413In Stock
200 mg$589In Stock
1 mL x 10 mM (in DMSO)$88In Stock
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Purity:99.94%
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Product Introduction

Bioactivity
Description
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSC-LC cells with KRAS mutation but not normal lung cells
AliasDUN09716
Chemical Properties
Molecular Weight292.81
FormulaC13H9ClN2S2
Cas No.300809-71-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 230 mg/mL (785.49 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4152 mL17.0759 mL34.1518 mL170.7592 mL
5 mM0.6830 mL3.4152 mL6.8304 mL34.1518 mL
10 mM0.3415 mL1.7076 mL3.4152 mL17.0759 mL
20 mM0.1708 mL0.8538 mL1.7076 mL8.5380 mL
50 mM0.0683 mL0.3415 mL0.6830 mL3.4152 mL
100 mM0.0342 mL0.1708 mL0.3415 mL1.7076 mL

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