T39275 |
Befotertinib
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D-0316 |
EGFR
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Befotertinib is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cel... |
T36404L |
PRLX-93936 HCL
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PRLX-93936 hcl(903499-49-0 Free base) |
Reactive Oxygen Species
,
Ferroptosis
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PRLX-93936 hcl is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) c... |
T60076 |
Oritinib
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SH-1028 |
EGFR
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Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q... |
T27837 |
Linzagolix
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GNRH Receptor
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Linzagolix is an antagonist of gonadotrophin releasing hormone (GnRH) . |
T9754 |
BLU-945
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BLU 945 , BLU945 |
EGFR
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BLU-945 is a potent, highly selective, reversible and orally active inhibitor of epidermal growth factor receptor (EGFR... |
T34891 |
TLI3-12
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TLI312 |
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TLI3-12 is the first small molecule degrader. It induces anaplastic lymphoma kinase (ALK) degradation, including that in... |
T40033 |
CD73-IN-5
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CD73-IN-5 is a potent and selective non-nucleotide small molecule inhibitor of CD73 ( IC 50 = 19 nM). |
TN4177 |
Gypenoside LI
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Others
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Gypenoside LI possesses non-small cell lung carcinoma A549 cell inhibitory activity. |
T41028 |
α-Glucosidase
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α-D-Glucosidase |
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α-Glucosidase (α-D-Glucosidase), a carbohydrate hydrolyzing enzyme, catalyzes the liberation of α-glucose from the non-r... |
T22343 |
HKB99
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Others
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HKB99, an allosteric inhibitor of phosphoglycerate mutase 1, could suppresse tumor growth and metastasis and overcome er... |
T60319 |
AZ8838
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AZ8838 is an effective, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pK i... |
T13014L |
STING agonist-3 trihydrochloride
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STING agonist-3 trihydrochloride (2138299-29-1 free base) |
Others
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STING agonist-3 trihydrochloride is a selective and non-nucleotide agonist of small-molecule STING(pEC50 and pEC50 of 7... |
T39109 |
ML338
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ML338 is a selective small molecule inhibitor probe of non-replicating Mycobacterium tuberculosis bacilli and is against... |
T36449 |
(S)-α-Methylbenzyl Ricinoleamide
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(S)-α-Methylbenzyl ricinoleamide is a fatty acid amide derived from ricinoleic acid and methyl benzylamine. It demonstra... |
T11009 |
Destruxin B
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Others
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Destruxin B is a cyclic peptide with insecticidal and anticancer activity isolated from the insect pathogenic fungus Met... |
T38978 |
CYH33
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CYH33 is an orally active, highly selective PI3Kα inhibitor with IC 50 s of 5.9 nM/598 nM/78.7 nM/225 nM against α/β/δ/γ... |
T40303 |
5-A-RU-PABC-Val-Cit-Fmoc
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5-A-RU-PABC-Val-Cit-Fmoc is the prodrug of 5-A-RU. 5-A-RU, a precursor of bacterial Riboflavin, is a mucosal-associated ... |
T38979 |
CYH33 methanesulfonate
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CYH33 methanesulfonate is an orally active, highly selective PI3Kα inhibitor with IC 50 s of 5.9 nM/598 nM/78.7 nM/225 n... |
T39664 |
Ethaselen
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BBSKE |
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Ethaselen (BBSKE) is an orally active, selective thioredoxin reductase (TrxR) inhibitor with IC 50 s of 0.5 and 0.35 μM ... |
T15019L |
CUR61414 hydrochloride
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CUR61414 hydrochloride (334998-36-6 Free base) |
Hedgehog/Smoothened
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CUR61414 is a potent and cell permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM). CUR61414 is a small-... |