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Befotertinib

🥰Excellent
Catalog No. T39275Cas No. 1835667-63-4
Alias D-0316, Befotertinib

Befotertinib (D-0316) is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cell lung cancer.

Befotertinib

Befotertinib

🥰Excellent
Purity: 99.40%
Catalog No. T39275Alias D-0316, BefotertinibCas No. 1835667-63-4
Befotertinib (D-0316) is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cell lung cancer.
Pack SizePriceAvailabilityQuantity
1 mg$81In Stock
5 mg$197In Stock
10 mg$313In Stock
25 mg$553In Stock
50 mg$787In Stock
100 mg$1,080In Stock
1 mL x 10 mM (in DMSO)$247In Stock
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Purity:99.40%
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Product Introduction

Bioactivity
Description
Befotertinib (D-0316) is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cell lung cancer.
AliasD-0316, Befotertinib
Chemical Properties
Molecular Weight567.61
FormulaC29H32F3N7O2
Cas No.1835667-63-4
SmilesCOc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(CC(F)(F)F)c2ccccc12
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (105.71 mM), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7618 mL8.8089 mL17.6177 mL88.0887 mL
5 mM0.3524 mL1.7618 mL3.5235 mL17.6177 mL
10 mM0.1762 mL0.8809 mL1.7618 mL8.8089 mL
20 mM0.0881 mL0.4404 mL0.8809 mL4.4044 mL
50 mM0.0352 mL0.1762 mL0.3524 mL1.7618 mL
100 mM0.0176 mL0.0881 mL0.1762 mL0.8809 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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