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Luliconazole

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Catalog No. T2411Cas No. 187164-19-8
Alias NND 502

Luliconazole (NND 502) is an Azole Antifungal. The mechanism of action of luliconazole is as a Cytochrome P450 2C19 Inhibitor.

Luliconazole

Luliconazole

🥰Excellent
Purity: 99.38%
Catalog No. T2411Alias NND 502Cas No. 187164-19-8
Luliconazole (NND 502) is an Azole Antifungal. The mechanism of action of luliconazole is as a Cytochrome P450 2C19 Inhibitor.
Pack SizePriceAvailabilityQuantity
25 mg$36In Stock
50 mg$52In Stock
1 mL x 10 mM (in DMSO)$58In Stock
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Purity:99.38%
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Product Introduction

Bioactivity
Description
Luliconazole (NND 502) is an Azole Antifungal. The mechanism of action of luliconazole is as a Cytochrome P450 2C19 Inhibitor.
In vitro
Luliconazole inhibits the growth of all filamentous fungi (except Saccharomyces cerevisiae) (MIC,≦0.004-0.125 μg/ml), Candida albicans (MIC range: 0.031-0.13 mg/ml), Trichophyton rubrum (MIC,≦0.00012-0.002 mg/ml).
In vivo
Luliconazole inhibits the growth of all filamentous fungi (except Saccharomyces cerevisiae) (MIC,≦0.004-0.125 μg/ml), Candida albicans (MIC range: 0.031-0.13 mg/ml), Trichophyton rubrum (MIC,≦0.00012-0.002 mg/ml).
AliasNND 502
Chemical Properties
Molecular Weight354.28
FormulaC14H9Cl2N3S2
Cas No.187164-19-8
SmilesClc1ccc([C@@H]2CS\C(S2)=C(\C#N)n2ccnc2)c(Cl)c1
Relative Density.1.52 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 66 mg/mL (186.3 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 5 mg/mL (14.11 mM)
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.8226 mL14.1131 mL28.2263 mL141.1313 mL
5 mM0.5645 mL2.8226 mL5.6453 mL28.2263 mL
10 mM0.2823 mL1.4113 mL2.8226 mL14.1131 mL
DMSO
1mg5mg10mg50mg
20 mM0.1411 mL0.7057 mL1.4113 mL7.0566 mL
50 mM0.0565 mL0.2823 mL0.5645 mL2.8226 mL
100 mM0.0282 mL0.1411 mL0.2823 mL1.4113 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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