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M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $169 | In Stock | |
5 mg | $428 | In Stock | |
10 mg | $591 | In Stock | |
25 mg | $868 | In Stock | |
50 mg | $1,180 | In Stock | |
100 mg | $1,630 | In Stock | |
1 mL x 10 mM (in DMSO) | $598 | In Stock |
Description | M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia. |
Targets&IC50 | Menin-MLL:1.4 nM (kd) |
Molecular Weight | 657.87 |
Formula | C37H47N5O4S |
Cas No. | 2363165-42-6 |
Smiles | CNC(=O)O[C@H]1CCC[C@@H]1[C@@]1(CN(C)Cc2ccccc12)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1 |
Relative Density. | 1.31 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 7 mg/mL (10.64 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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