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Mitoquinone mesylate

🥰Excellent
Catalog No. T12059LCas No. 845959-50-4
Alias MitoQ10 mesylate, MitoQ mesylate

Mitoquinone mesylate (MitoQ10 mesylate) is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.

Mitoquinone mesylate

Mitoquinone mesylate

🥰Excellent
Purity: 97.12%
Catalog No. T12059LAlias MitoQ10 mesylate, MitoQ mesylateCas No. 845959-50-4
Mitoquinone mesylate (MitoQ10 mesylate) is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.
Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
5 mg$72In Stock
10 mg$113In Stock
25 mg$228In Stock
50 mg$372In Stock
100 mg$549In Stock
500 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$109In Stock
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Purity:97.12%
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Product Introduction

Bioactivity
Description
Mitoquinone mesylate (MitoQ10 mesylate) is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.
In vitro
Normal rat kidney (NRK) cells exposed to CS result in a ~2-fold increase in fluorescence due to mitochondrial superoxide compared with untreated cells. Mitoquinone offers significant protection against CS-induced mitochondrial superoxide generation[1].
In vivo
Mitoquinone (MitoQ) treatment nearly doubles lung MPO activity induced by Caerulein with a significant increase of serum IL-6 levels also evident at 10?mg/kg (dose 1)[2].
AliasMitoQ10 mesylate, MitoQ mesylate
Chemical Properties
Molecular Weight678.81
FormulaC38H47O7PS
Cas No.845959-50-4
Smiles[O-]S(=O)(C)=O.O=C(C(CCCCCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=C4C)C(OC)=C(OC)C4=O
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (73.66 mM), Sonication is recommended.
H2O: 10 mg/mL (14.73 mM), Sonication are recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.4732 mL7.3658 mL14.7317 mL73.6583 mL
5 mM0.2946 mL1.4732 mL2.9463 mL14.7317 mL
10 mM0.1473 mL0.7366 mL1.4732 mL7.3658 mL
DMSO
1mg5mg10mg50mg
20 mM0.0737 mL0.3683 mL0.7366 mL3.6829 mL
50 mM0.0295 mL0.1473 mL0.2946 mL1.4732 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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