Shopping Cart
- Remove All
Your shopping cart is currently empty
MT189
🥰Excellent
Catalog No. T60129Cas No. 1885900-35-5
Alias Antiproliferative agent-14
MT189 (Antiproliferative agent-14) is a potent tubulin polymerization inhibitor, with an IC50 of 3.41 μM. Antiproliferative agent-14 has excellent antiproliferative activity. Antiproliferative agent-14 possess the ability to arrest cells at G2/M phases of the cell cycle.
MT189
🥰Excellent
Purity: 98.67%
Catalog No. T60129Alias Antiproliferative agent-14Cas No. 1885900-35-5
MT189 (Antiproliferative agent-14) is a potent tubulin polymerization inhibitor, with an IC50 of 3.41 μM. Antiproliferative agent-14 has excellent antiproliferative activity. Antiproliferative agent-14 possess the ability to arrest cells at G2/M phases of the cell cycle.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $31 | In Stock | |
| 5 mg | $53 | In Stock | |
| 10 mg | $82 | In Stock | |
| 25 mg | $166 | In Stock | |
| 50 mg | $238 | In Stock | |
| 100 mg | $350 | In Stock | |
| 200 mg | $479 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "MT189"
Methylene Blue trihydrate
Methylthionine chloride, Methylene Blue, Basic blue 9
T00067220-79-3
Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene Blue trihydrate is used as a bacteriologic stain and as an indicator. It inhibits soluble guanylyl cyclase and has been used to treat cyanide poisoning and to lower levels of methemoglobin. It also inhibits tau filament formation (IC50: 1.9μM).
- $42
Size
QTY
Flubendazole
NSC 313680, Fluvermal, Flumoxane, Flumoxanal
T000931430-15-6
Flubendazole (Flumoxane) is available OTC in Europe that is an anthelmintic using to treat worm infection in humans.
- $50
Size
QTY
Griseofulvin
Grisactin, Fulvicin, Amudane
T1382126-07-8
Griseofulvin (Fulvicin) is an antifungal agent used in the treatment of TINEA infections.
- $40
Size
QTY
4-Isopropoxybenzoic acid
AI3-12104, AI312104, AI3 12104
T2497713205-46-4
4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.
- $34
Size
QTY
Oxfendazole
RS-8858
T071453716-50-0
Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.
- $31
Size
QTY
N-Phenylbenzylamine
Benzylaniline, Benzenemethanamine
T0651103-32-2
A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization
- $29
Size
QTY
Mebendazole
Cited
Vermox, Telmin, Pantelmin, Mebenvet
T115531431-39-7
Mebendazole (Mebenvet) is a hedgehog inhibitor, used as an antihelminthic.
- $31
Size
QTY
Cited4'-Demethylepipodophyllotoxin
DMEP, 4'-O-demethylepipodophyllotoxin, 4'-DMEP, 4-Demethylepipodophyllotoxin
T29376559-91-7
4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly.
- $33
Size
QTY
Paclitaxel
Cited
Taxol, NSC 125973
T096833069-62-4
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.
- $34
Size
QTY
CitedMethylene Blue Cited
Tetramethylthionine chloride, methylthioninium chloride, CI-52015, Basic Blue 9
T688861-73-4
Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dye in chromoendoscopy.
- $30
Size
QTY
CitedThiabendazole
2-(4-Thiazolyl)benzimidazole
T0938148-79-8
Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.
- $29
Size
QTY
Docetaxel Cited
RP-56976, NSC 628503
T1034114977-28-5
Docetaxel (RP-56976), a semi-synthetic analog of paclitaxel, is a microtubule depolymerization inhibitor (IC50=0.2 μM) that attenuates the effects of bcl-2 and bcl-xL gene expression and exhibits apoptosis-inducing, anti-tumor activity.
- $30
Size
QTY
CitedSelect Batch
Purity:98.67%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | MT189 (Antiproliferative agent-14) is a potent tubulin polymerization inhibitor, with an IC50 of 3.41 μM. Antiproliferative agent-14 has excellent antiproliferative activity. Antiproliferative agent-14 possess the ability to arrest cells at G2/M phases of the cell cycle. |
| In vitro | MT189 shows antiproliferative activity against HeLa cell (IC50=13 nM). Antiproliferative agent-14 shows inhibition of colchicine binding activity, with 72.2% inhibitory percentage[1]. |
| Alias | Antiproliferative agent-14 |
| Molecular Weight | 363.38 |
| Formula | C21H18FN3O2 |
| Cas No. | 1885900-35-5 |
| Smiles | COc1ccc(CNc2c(nc3ccc(F)cn23)-c2ccccc2O)cc1 |
| Relative Density. | 1.28 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90 mg/mL (247.7 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy MT189 | purchase MT189 | MT189 cost | order MT189 | MT189 chemical structure | MT189 in vitro | MT189 formula | MT189 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.