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ACSS2-IN-2

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Purity:99.54%

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COA HNMR LCMS

ACSS2-IN-2

Catalog No. T60060Cas No. 2332820-04-7

ACSS2-IN-2 (MTB-9655) is an inhibitor of acyl-CoA synthetase short-chain family member 2 (ACSS2). ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer.

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Pack Size	Price	Availability
1 mg	$51	In Stock
2 mg	$74	In Stock
5 mg	$122	In Stock
10 mg	$197	In Stock
25 mg	$372	In Stock
50 mg	$578	In Stock
100 mg	$833	In Stock
1 mL x 10 mM (in DMSO)	$133	In Stock

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Product Introduction

Bioactivity

Description	ACSS2-IN-2 (MTB-9655) is an inhibitor of acyl-CoA synthetase short-chain family member 2 (ACSS2). ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer.
In vitro	ACSS2-IN-2 (Compound 261) (5 h) exhibits ACSS2 inhibitory activity with an IC50 of 3.8 nM in MDA-MB-468 cells.'
Alias	MTB-9655

Chemical Properties

Molecular Weight	415.39
Formula	C21H19F2N3O4
Cas No.	2332820-04-7

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 90 mg/mL (216.7 mM), Sonication and heating to 60℃ are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4074 mL	12.0369 mL	24.0738 mL	120.3688 mL
5 mM	0.4815 mL	2.4074 mL	4.8148 mL	24.0738 mL
10 mM	0.2407 mL	1.2037 mL	2.4074 mL	12.0369 mL
20 mM	0.1204 mL	0.6018 mL	1.2037 mL	6.0184 mL
50 mM	0.0481 mL	0.2407 mL	0.4815 mL	2.4074 mL
100 mM	0.0241 mL	0.1204 mL	0.2407 mL	1.2037 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc