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Muscimol hydrochloride
😃Good
Catalog No. T73608Cas No. 3579-03-1
Alias Agarine hydrochloride, Agarin hydrochloride
Muscimol hydrochloride is the salt form of Muscimol, the main psychoactive component of Amanita muscaria, a potent and selective GABAA receptor agonist and partial GABAC receptor agonist, with no activity on GABAB receptors. It is commonly used in central neuroscience research, with analgesic, anxiolytic and neuroprotective effects, with the advantage of being able to cross the blood-brain barrier and can be taken orally.
Muscimol hydrochloride
😃Good
Purity: 95%
Catalog No. T73608Alias Agarine hydrochloride, Agarin hydrochlorideCas No. 3579-03-1
Muscimol hydrochloride is the salt form of Muscimol, the main psychoactive component of Amanita muscaria, a potent and selective GABAA receptor agonist and partial GABAC receptor agonist, with no activity on GABAB receptors. It is commonly used in central neuroscience research, with analgesic, anxiolytic and neuroprotective effects, with the advantage of being able to cross the blood-brain barrier and can be taken orally.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | In Stock | |
| 50 mg | Inquiry | Backorder |
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CitedSelect Batch
Purity:95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Muscimol hydrochloride is the salt form of Muscimol, the main psychoactive component of Amanita muscaria, a potent and selective GABAA receptor agonist and partial GABAC receptor agonist, with no activity on GABAB receptors. It is commonly used in central neuroscience research, with analgesic, anxiolytic and neuroprotective effects, with the advantage of being able to cross the blood-brain barrier and can be taken orally. |
| In vitro | Methods: A human 3D skin model was treated with NIBR-LTSi (1, 3, 10 μM, 3 days) to evaluate its proliferative effects. Results: NIBR-LTSi treatment resulted in a dose-dependent increase in keratinocyte proliferation. In addition, NIBR-LTSi-induced YAP signaling impeded the differentiation of human keratinocytes. [1] |
| In vivo | Methods: Mice were treated with NIBR-LTSi (30, 100 mg/kg, oral administration) to study the later stages of liver regeneration. Results: NIBR-LTSi resulted in significant dose-dependent growth of organoids starting 48 hours after initial treatment and showed reduced expression of the mature podocyte marker WT1 and increased serum blood urea nitrogen (BUN) levels. [1] |
| Alias | Agarine hydrochloride, Agarin hydrochloride |
| Molecular Weight | 150.56 |
| Formula | C4H7ClN2O2 |
| Cas No. | 3579-03-1 |
| Smiles | Cl.NCc1cc(=O)[nH]o1 |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture | store at 4°C | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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