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N-Desethyl amodiaquine dihydrochloride

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Catalog No. T12154LCas No. 79049-30-2

N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.

N-Desethyl amodiaquine dihydrochloride

N-Desethyl amodiaquine dihydrochloride

🥰Excellent
Purity: 98.83%
Catalog No. T12154LCas No. 79049-30-2
N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.
Pack SizePriceAvailabilityQuantity
1 mg$115In Stock
5 mg$247In Stock
10 mg$455In Stock
25 mg$753In Stock
50 mg$1,060In Stock
100 mg$1,430In Stock
500 mg$2,860In Stock
1 mL x 10 mM (in DMSO)$272In Stock
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Purity:98.83%
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Product Introduction

Bioactivity
Description
N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.
Chemical Properties
Molecular Weight400.73
FormulaC18H20Cl3N3O
Cas No.79049-30-2
SmilesCl.Cl.CCNCc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (149.73 mM), Sonication is recommended.
H2O: 100 mg/mL (249.54 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.4954 mL12.4772 mL24.9545 mL124.7723 mL
5 mM0.4991 mL2.4954 mL4.9909 mL24.9545 mL
10 mM0.2495 mL1.2477 mL2.4954 mL12.4772 mL
20 mM0.1248 mL0.6239 mL1.2477 mL6.2386 mL
50 mM0.0499 mL0.2495 mL0.4991 mL2.4954 mL
100 mM0.0250 mL0.1248 mL0.2495 mL1.2477 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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