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NBI-31772

Catalog No. T8906   CAS 374620-70-9
Synonyms: NBI31772, NBI 31772

NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM). NBI-31772 can be used in research on IGF-responsive diseases.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
NBI-31772 Chemical Structure
NBI-31772, CAS 374620-70-9
Pack Size Availability Price/USD Quantity
1 mg In stock $ 51.00
2 mg In stock $ 74.00
5 mg In stock $ 122.00
10 mg In stock $ 197.00
25 mg In stock $ 428.00
50 mg In stock $ 639.00
100 mg In stock $ 890.00
1 mL * 10 mM (in DMSO) In stock $ 179.00
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Purity: 99.83%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM). NBI-31772 can be used in research on IGF-responsive diseases.
Synonyms NBI31772, NBI 31772
Molecular Weight 341.27
Formula C17H11NO7
CAS No. 374620-70-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 120 mg/mL (351.62 mM), sonification is recommended.

TargetMolReferences and Literature

1. Rinker TE, et al. Microparticle-mediated sequestration of cell-secreted proteins to modulate chondrocytic differentiation. Acta Biomater. 2017 Dec 30. pii: S1742-7061(17)30804-8. 2. Safian D, et al. Follicle-Stimulating Hormone Regulates igfbp Gene Expression Directly or via Downstream Effectors to Modulate Igf3 Effects on Zebrafish Spermatogenesis. Front Endocrinol (Lausanne). 2017 Nov 20;8:328. 3. Lékó AH, et al. Insulin-like growth factor I and its binding protein-3 are regulators of lactation and maternal responsiveness. Sci Rep. 2017 Jun 13;7(1):3396. 4. Safian D, et al. Igf Binding Proteins Protect Undifferentiated Spermatogonia in the Zebrafish Testis Against Excessive Differentiation. Endocrinology. 2016 Nov;157(11):4423-4433. Epub 2016 Sep 30.

Related compound libraries

This product is contained In the following compound libraries:
Tyrosine Kinase Inhibitor Library Bioactive Compounds Library Max Bioactive Compound Library Inhibitor Library Metabolism Compound Library ReFRAME Related Library Anti-Aging Compound Library Kinase Inhibitor Library

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Keywords

NBI-31772 374620-70-9 Tyrosine Kinase/Adaptors IGF-1R inhibit NBI31772 IGF-responsive diseases IGFBP NBI 31772 Inhibitor inhibitor

 

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