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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $113 | In Stock | |
2 mg | $166 | In Stock | |
5 mg | $278 | In Stock | |
10 mg | $455 | In Stock | |
25 mg | $787 | In Stock | |
50 mg | $1,160 | In Stock | |
100 mg | $1,620 | In Stock | |
1 mL x 10 mM (in DMSO) | $297 | In Stock |
Description | NCGC00029283 is a potent inhibitor of Werner syndrome helicase-nuclease (WRN), displaying inhibitory activity against WRN helicase with an IC 50 value of 2.3 μM. Additionally, it exhibits inhibitory effects on Bloom syndrome protein helicase (BLM) and Fanconi anemia group J protein helicase (FANCJ) with IC 50 values of 12.5 μM and 3.4 μM, respectively. |
In vitro | NCGC00029283 (0-100 μM; 24-72 h) effectively blocks cell proliferation in U2-OS cells[1]. |
Molecular Weight | 337.3 |
Formula | C18H12FN3O3 |
Cas No. | 714240-31-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||
Solubility Information | DMSO: 6.3 mg/mL (18.7 mM) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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