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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $64 | In Stock | |
5 mg | $198 | In Stock | |
10 mg | $372 | In Stock | |
25 mg | $689 | In Stock | |
50 mg | $987 | In Stock | |
100 mg | $1,530 | In Stock | |
500 mg | $2,970 | In Stock | |
1 mL x 10 mM (in DMSO) | $173 | In Stock |
Description | Nelonemdaz (Neu2000) is an NMDA receptor antagonist with antioxidant activity and neuroprotective activity used in the study of cerebral infarction reperfusion injury and acute ischemic stroke. |
In vitro | Nelonemdaz (0.19-12.5 μM) dose-dependently reduces the amount of reactive oxygen species/nitrogen species (ROS/RNS) formation induced by Antimycin A and inhibits the formation of malondialdehyde (MDA)[3]. |
In vivo | In male Sprague-Dawley rats weighing 260 to 300 g (subjected to the clip occlusion model), Nelonemdaz (0.5-20 mg/kg; intravenous administration 5 minutes after reperfusion) exhibited significant neuroprotective effects[1]. |
Alias | Salfaprodil free base, Neu2000 |
Molecular Weight | 383.22 |
Formula | C15H8F7NO3 |
Cas No. | 640290-67-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (260.95 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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