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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $34 | In Stock | |
5 mg | $55 | In Stock | |
10 mg | $93 | In Stock | |
25 mg | $197 | In Stock | |
50 mg | $369 | In Stock | |
100 mg | $549 | In Stock | |
500 mg | $1,190 | In Stock | |
1 mL x 10 mM (in DMSO) | $61 | In Stock |
Description | PF-6274484, a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM, inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells with IC50 of 5.8 nM and 6.6 nM, respectively. |
Targets&IC50 | EGFR:0.14 nM(ki) |
Alias | PF 6274484 |
Molecular Weight | 372.78 |
Formula | C18H14ClFN4O2 |
Cas No. | 1035638-91-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 65 mg/ml (174.36 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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