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Pimonidazole

🥰Excellent
Catalog No. T16537Cas No. 70132-50-2

Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group. It can be used for qualitative and quantitative assessment of tumor hypoxia. Pimonidazole is a novel hypoxia marker for the complementary study of tumor hypoxia and cell proliferation in tumors.

Pimonidazole

Pimonidazole

🥰Excellent
Purity: 99.57%
Catalog No. T16537Cas No. 70132-50-2
Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group. It can be used for qualitative and quantitative assessment of tumor hypoxia. Pimonidazole is a novel hypoxia marker for the complementary study of tumor hypoxia and cell proliferation in tumors.
Pack SizePriceAvailabilityQuantity
10 mg37 €In Stock
25 mg76 €In Stock
50 mg145 €In Stock
100 mg274 €In Stock
200 mg375 €In Stock
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Purity:99.57%
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Product Introduction

Bioactivity
Description
Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group. It can be used for qualitative and quantitative assessment of tumor hypoxia. Pimonidazole is a n
Chemical Properties
Molecular Weight254.29
FormulaC11H18N4O3
Cas No.70132-50-2
SmilesOC(CN1CCCCC1)Cn1ccnc1[N+]([O-])=O
Relative Density.1.39g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (235.95 mM)
H2O: 1 mg/mL (3.93 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM3.9325 mL19.6626 mL39.3252 mL196.6259 mL
DMSO
1mg5mg10mg50mg
5 mM0.7865 mL3.9325 mL7.8650 mL39.3252 mL
10 mM0.3933 mL1.9663 mL3.9325 mL19.6626 mL
20 mM0.1966 mL0.9831 mL1.9663 mL9.8313 mL
50 mM0.0787 mL0.3933 mL0.7865 mL3.9325 mL
100 mM0.0393 mL0.1966 mL0.3933 mL1.9663 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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