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pimpinellin

Catalog No. T5776 CAS 131-12-4

Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.

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pimpinellin, CAS 131-12-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 89.00
5 mg	In stock	$ 193.00
10 mg	In stock	$ 328.00
25 mg	In stock	$ 553.00
50 mg	In stock	$ 789.00
100 mg	In stock	$ 1,070.00

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Purity: 99.85%

Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.
In vitro	Pimpinellin had potent cytotoxic activities against the three cell lines, with the IC50 values of 14.4?±?0.3?μM, 20.4?±?0.5?μM, and 29.2?±?0.6?μM, respectively. The mechanism of the antitumor action indicated that pimpinellin inhibited the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72?h of treatment at 20?μM.
Source	Natural Products > Fabaceae > Psoralea

Molecular Weight	246.22
Formula	C13H10O5
CAS No.	131-12-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 49 mg/mL (199.0 mM)

References and Literature

1. Yang S , Liu M , Liang N , et al. Discovery and antitumor activities of constituents fromCyrtomium fortumei(J.) Smith rhizomes[J]. Chemistry Central Journal, 2013, 7(1):24.

Citations

1. Li S, Kelly C, Knob R, et al.Analysis of Coumarin-Based Phototoxins in Citrus-Derived Essential Oils Using Liquid Chromatography-Mass Spectrometry.Chromatographia.2023: 1-11.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Inhibitor Library Miao medicine Compound Library Anti-Neurodegenerative Disease Compound Library Anti-Alzheimer's Disease Compound Library Selected Plant-Sourced Compound Library Bioactive Compounds Library Max Apoptosis Compound Library Human Metabolite Library Natural Product Library

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Keywords

pimpinellin 131-12-4 Apoptosis Microbiology/Virology Anti-infection inhibit Inhibitor inhibitor

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