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RAD51-IN-1

🥰Excellent
Catalog No. T9271Cas No. 2101739-18-6

Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.

RAD51-IN-1

RAD51-IN-1

🥰Excellent
Purity: 99.87%
Catalog No. T9271Cas No. 2101739-18-6
Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.
Pack SizePriceAvailabilityQuantity
2 mg$34In Stock
5 mg$55In Stock
10 mg$89In Stock
25 mg$178In Stock
50 mg$297In Stock
100 mg$478In Stock
1 mL x 10 mM (in DMSO)$61In Stock
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Purity:99.87%
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Product Introduction

Bioactivity
Description
Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.
In vitro
RAD51-IN-1(10μM) decreases the ratio of RAD51 positive cells/cH2AX postive cells in MDA-MB-231 cell exposure to 6 Gy irradiation. RAD51-IN-1 (10μM) significantly inhibits DNA damage induced RAD51 foci formation with 6 Gy irradiation.[1]
Chemical Properties
Molecular Weight373.83
FormulaC22H16ClN3O
Cas No.2101739-18-6
SmilesClc1ccc(Cn2c(\C=C\c3cccnc3)nc3ccccc3c2=O)cc1
Relative Density.1.24 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 27.5 mg/ml (73.56 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6750 mL13.3751 mL26.7501 mL133.7506 mL
5 mM0.5350 mL2.6750 mL5.3500 mL26.7501 mL
10 mM0.2675 mL1.3375 mL2.6750 mL13.3751 mL
20 mM0.1338 mL0.6688 mL1.3375 mL6.6875 mL
50 mM0.0535 mL0.2675 mL0.5350 mL2.6750 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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