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Ravuconazole

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Purity:99.86%

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COA HNMR HPLC

Ravuconazole

Catalog No. T7152Cas No. 182760-06-1

Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.

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Pack Size	Price	Availability
2 mg	$31	In Stock
5 mg	$56	In Stock
10 mg	$98	In Stock
25 mg	$222	In Stock
50 mg	$396	In Stock
100 mg	$579	In Stock
1 mL x 10 mM (in DMSO)	$62	In Stock

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Product Introduction

Bioactivity

Description	Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.
In vitro	The in vitro activity of BMS-207147 against 80 clinical isolates of Aspergillus was compared with that of itraconazole and amphotericin B, using a validated microtiter method.?Geometric mean MICs (in microg/ml) were as follows: 1.71 for BMS-207147, 0.67 for itraconazole, and 0.63 for amphotericin B. The range of concentrations of each drug was 0.125 to >16 microg/ml.?Aspergillus fumigatus was significantly more susceptible to BMS-207147 (P < 0.?05) than A. terreus and A. flavus.?No BMS-207147-resistant A. fumigatus isolates were identified, though eight itraconazole-resistant (MIC, >8 microg/ml) isolates were.?BMS-207147 is active against Aspergillus spp. at slightly high concentrations compared with itraconazole and amphotericin B[1].
Alias	BMS-207147, ER-30346

Chemical Properties

Molecular Weight	437.47
Formula	C22H17F2N5OS
Cas No.	182760-06-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (114.29 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2859 mL	11.4294 mL	22.8587 mL	114.2936 mL
5 mM	0.4572 mL	2.2859 mL	4.5717 mL	22.8587 mL
10 mM	0.2286 mL	1.1429 mL	2.2859 mL	11.4294 mL
20 mM	0.1143 mL	0.5715 mL	1.1429 mL	5.7147 mL
50 mM	0.0457 mL	0.2286 mL	0.4572 mL	2.2859 mL
100 mM	0.0229 mL	0.1143 mL	0.2286 mL	1.1429 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

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