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Ravuconazole

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Catalog No. T7152Cas No. 182760-06-1
Alias ER-30346, BMS-207147

Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.

Ravuconazole

Ravuconazole

🥰Excellent
Purity: 99.84%
Catalog No. T7152Alias ER-30346, BMS-207147Cas No. 182760-06-1
Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.
Pack SizePriceAvailabilityQuantity
5 mg$34In Stock
10 mg$59In Stock
25 mg$133In Stock
50 mg$238In Stock
100 mg$347In Stock
200 mg$497In Stock
1 mL x 10 mM (in DMSO)$37In Stock
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Purity:99.84%
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Product Introduction

Bioactivity
Description
Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.
In vitro
The in vitro activity of Ravuconazole against 80 clinical isolates of Aspergillus was compared with that of itraconazole and amphotericin B, using a validated microtiter method.Geometric mean MICs (in microg/ml) were as follows: 1.71 for Ravuconazole, 0.67 for itraconazole, and 0.63 for amphotericin B. The range of concentrations of each drug was 0.125 to >16 microg/ml.Aspergillus fumigatus was significantly more susceptible to Ravuconazole (P < 0.05) than A. terreus and A. flavus.No Ravuconazole-resistant A. fumigatus isolates were identified, though eight itraconazole-resistant (MIC, >8 microg/ml) isolates were.Ravuconazole is active against Aspergillus spp. at slightly high concentrations compared with itraconazole and amphotericin B[1].
AliasER-30346, BMS-207147
Chemical Properties
Molecular Weight437.47
FormulaC22H17F2N5OS
Cas No.182760-06-1
SmilesC[C@@H](c1nc(cs1)-c1ccc(cc1)C#N)[C@](O)(Cn1cncn1)c1ccc(F)cc1F
Relative Density.1.38g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (114.29 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2859 mL11.4294 mL22.8587 mL114.2936 mL
5 mM0.4572 mL2.2859 mL4.5717 mL22.8587 mL
10 mM0.2286 mL1.1429 mL2.2859 mL11.4294 mL
20 mM0.1143 mL0.5715 mL1.1429 mL5.7147 mL
50 mM0.0457 mL0.2286 mL0.4572 mL2.2859 mL
100 mM0.0229 mL0.1143 mL0.2286 mL1.1429 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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