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Rho-Kinase-IN-1

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Catalog No. T12721Cas No. 1035094-83-7

Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation diseases.

Rho-Kinase-IN-1

Rho-Kinase-IN-1

🥰Excellent
Purity: 99.51%
Catalog No. T12721Cas No. 1035094-83-7
Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation diseases.
Pack SizePriceAvailabilityQuantity
1 mg64 €In Stock
5 mg140 €In Stock
10 mg215 €In Stock
25 mg377 €In Stock
50 mg529 €In Stock
100 mg701 €In Stock
200 mg943 €In Stock
1 mL x 10 mM (in DMSO)107 €In Stock
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Purity:99.51%
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Product Introduction

Bioactivity
Description
Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation diseases.
Targets&IC50
ROCK2:3.9 nM (ki), ROCK1:30.5 nM (ki)
Chemical Properties
Molecular Weight352.5
FormulaC20H24N4S
Cas No.1035094-83-7
SmilesCSc1ccc(CN2CCCC(C2)Nc2ccc3[nH]ncc3c2)cc1
Relative Density.1.25 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 65 mg/mL (184.4 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8369 mL14.1844 mL28.3688 mL141.8440 mL
5 mM0.5674 mL2.8369 mL5.6738 mL28.3688 mL
10 mM0.2837 mL1.4184 mL2.8369 mL14.1844 mL
20 mM0.1418 mL0.7092 mL1.4184 mL7.0922 mL
50 mM0.0567 mL0.2837 mL0.5674 mL2.8369 mL
100 mM0.0284 mL0.1418 mL0.2837 mL1.4184 mL

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