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Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $31 | In Stock | |
25 mg | $48 | In Stock | |
50 mg | $65 | In Stock | |
100 mg | $97 | In Stock | |
200 mg | $155 | In Stock | |
500 mg | $262 | In Stock |
Description | Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome. |
In vitro | Ribostamycin, as an intermediate in the biosynthesis of neomycin, can inhibit the chaperone activity of protein disulfide isomerase (PDI) but does not inhibit its isomerase activity. At a concentration of 256 µg/mL, it exhibits almost no toxicity to HUVEC cells. |
In vivo | Compared to other antibiotics, Ribostamycin (400 mg/kg/day) causes the lowest ototoxicity, as its drug concentration in the inner ear fluid of guinea pigs is relatively low. Ribostamycin exhibits the least ototoxicity to the cochlea and vestibular organs of guinea pigs. |
Alias | Vistamycin sulfate |
Molecular Weight | 552.55 |
Formula | C17H34N4O10·H2SO4 |
Cas No. | 53797-35-6 |
Smiles | OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O |
Relative Density. | 1.6g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: Insoluble H2O: 10 mM, Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O
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