Shopping Cart
- Remove All
Your shopping cart is currently empty
Argentina
Australia
Austria
Belgium
Brazil
Bulgaria
Croatia
Cyprus
Czech
Denmark
Egypt
Estonia
Finland
France
Germany
Greece
Hong Kong
Hungary
Iceland
India
Ireland
Israel
Italy
Japan
Korea
Latvia
Lebanon
Malaysia
Malta
Morocco
Netherlands
New Zealand
Norway
Poland
Portugal
Romania
Singapore
Slovakia
Slovenia
Spain
Sweden
Switzerland
Taiwan,China
Thailand
Turkey
United Kingdom
United States
Other Countries
Select your Country or Region
Rislenemdaz
Contact us for more batch information
Rislenemdaz
Catalog No. T12733Cas No. 808732-98-1
Rislenemdaz (CERC-301) (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $98 | In Stock | |
| 5 mg | $313 | In Stock | |
| 10 mg | $496 | In Stock | |
| 25 mg | $828 | In Stock | |
| 50 mg | $1,150 | In Stock | |
| 100 mg | $1,550 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $345 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Rislenemdaz"
(-)-Huperzine A
T3026102518-79-6
(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD).
- $43
Size
QTY
D-Cycloserine
T158968-41-7
D-Cycloserine (RO-1-9213) is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents.
- $43
Size
QTY
(S)-Willardiine
T1345621416-43-3In house
(S)-Willardiine (L-willardiine) is present in the seeds of Acacia and Mimosa. (S)-Willardiine is an AMPA/kainate receptor agonist (EC50 = 44.8 μM).
- $50
Size
QTY
AMPA receptor antagonist-3
T61813923272-18-8
AMPA receptor antagonist-3 is an AMPA receptor antagonist.
- $195
Size
QTY
NMDAR antagonist 1
T55222220162-06-9
NMDAR antagonist 1 is an orally active, NR2B-selective NMDAR antagonist.
- $71
Size
QTY
Coluracetam
T7591135463-81-9
Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.
- $31
Size
QTY
Orphenadrine hydrochloride
T1308341-69-5
Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
- $30
Size
QTY
Linalool
T2S226478-70-6
1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury through induction of antioxidant defense via Nrf2 activating and reduction inflammatory response via NF-κB inhibition. 3. Linalool biosynthesis and accumulation might be involved in plant defense against bacterial and fungal pathogens and be associated with field resistance to citrus canker. 4. Linalool significantly increased the expression of antioxidant enzymes regulated by Nrf-2 and diminished lung tissue levels of several pro-inflammatory cytokines, including tumor necrosis factor α (TNF-α) and interleukin (IL)-6.
- $29
Size
QTY
TAK-653
T615181358751-06-0
TAK-653, a selective positive allosteric modulator (PAM) of AMPA receptors exhibiting minimal agonistic activity, elicits an antidepressant-like response while maintaining a favorable safety profile in rat models.
- $41
Size
QTY
Tulrampator
T171791038984-31-4
Tulrampator (S-47445) is an orally bioavailable positive AMPAR with antidepressant effects.
- $32
Size
QTY
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Rislenemdaz (CERC-301) (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B). |
| In vitro | rislemdaz (CERC-301) inhibited calcium influx in agonist stimulated NMDA-GluN1a/GluN2B L(tk-) cells. rislemdaz (CERC-301) had an IC50 of 3.6 nM. rislemdaz is highly selective for GluN2B receptors. rislemdaz showed minimal activity against sigma-type receptors at a concentration of 10 uM[1]. |
| Alias | CERC-301, MK-0657 |
| Molecular Weight | 358.41 |
| Formula | C19H23FN4O2 |
| Cas No. | 808732-98-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90.0 mg/mL (251.1 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。 Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Dose Conversion
You can also refer to dose conversion for different animals. More
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.