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Robinetin

🥰Excellent
Catalog No. TN2158Cas No. 490-31-3
Alias 3,3',4',5',7-Pentahydroxyflavone

Robinetin (3,3',4',5',7-Pentahydroxyflavone) exhibits potent antioxidant and antiradical activities, effectively inhibiting EYPC membrane lipid peroxidation and HbA glycosylation.

Robinetin

Robinetin

🥰Excellent
Purity: 99.61%
Catalog No. TN2158Alias 3,3',4',5',7-PentahydroxyflavoneCas No. 490-31-3
Robinetin (3,3',4',5',7-Pentahydroxyflavone) exhibits potent antioxidant and antiradical activities, effectively inhibiting EYPC membrane lipid peroxidation and HbA glycosylation.
Pack SizePriceAvailabilityQuantity
1 mg$43In Stock
5 mg$97In Stock
10 mg$143In Stock
25 mg$238In Stock
50 mg$358In Stock
100 mg$528In Stock
1 mL x 10 mM (in DMSO)$97In Stock
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Purity:99.61%
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Product Introduction

Bioactivity
Description
Robinetin (3,3',4',5',7-Pentahydroxyflavone) exhibits potent antioxidant and antiradical activities, effectively inhibiting EYPC membrane lipid peroxidation and HbA glycosylation.
In vitro
Robinetin inhibits the DNA synthesis in Proteus vulgaris, and the RNA synthesis in S. aureus[2]. Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore[3]. Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner[4].
In vivo
Pretreatment with 0.5, 12.5 or 25 mumol robinetin resulted in elevated induction of epidermal ODC by TPA at 6 h after TPA. However, treatment with 50 or 100 mumol robinetin diminished ODC induction at 6 h after TPA[2]. Anti-mutagenicity was determined in the Salmonella typhimurium assay, Robinetin caused an 87% inhibition of mutagenicity by 2-aminoanthracene[2]
Alias3,3',4',5',7-Pentahydroxyflavone
Chemical Properties
Molecular Weight302.24
FormulaC15H10O7
Cas No.490-31-3
SmilesOc1ccc2c(c1)oc(-c1cc(O)c(O)c(O)c1)c(O)c2=O
Relative Density.1.3616 g/cm3 (Estimated)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (330.86 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3086 mL16.5431 mL33.0863 mL165.4314 mL
5 mM0.6617 mL3.3086 mL6.6173 mL33.0863 mL
10 mM0.3309 mL1.6543 mL3.3086 mL16.5431 mL
20 mM0.1654 mL0.8272 mL1.6543 mL8.2716 mL
50 mM0.0662 mL0.3309 mL0.6617 mL3.3086 mL
100 mM0.0331 mL0.1654 mL0.3309 mL1.6543 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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