Search Result

Search Results for " peroxidation "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T10166	Lipid peroxidation inhibitor 1		Others
	Lipid peroxidation inhibitor 1 is an inhibitor of lipid peroxidation (IC50: 0.07 μM).		Others
T8899	Metipranolol		Adrenergic Receptor
	Metipranolol (Betamann) is a type of β- Adrenergic receptors（ β- A potent antagonist of adrenergic receptor on guinea pig atria β 1- Adrenergic receptors and rat uterus β The 2-adrenergic receptor exhibited the beta bloc...		Adrenergic Receptor
T22022	Adaptaquin		HIF
	Adaptaquin is an inhibitor of the hypoxia-inducing factor prolyl hydroxylase (HIF-PH) [1] [2].		HIF
T0342	Carvedilol phosphate hemihydrate	Carvedilol phosphate,BM 14190 (phosphate hemihydrate)	VEGFR , Others , Potassium Channel , LDL , Integrin , Gap Junction Protein , NADPH , Adrenergic Receptor , Autophagy
	Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathom...
T9956	VK-28		Mitochondrial Metabolism , Lipid
	VK-28 is a brain permeable iron chelator with neuroprotection. VK-28 inhibits basal as well as iron-induced mitochondrial lipid peroxidation.		Mitochondrial Metabolism , Lipid
T60084	FINO2		Ferroptosis
	FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 i...		Ferroptosis
T5523	Imidazole ketone erastin	IKE	Ferroptosis
	Imidazole ketone erastin (IKE) is an iron death inducer with inhibitory effects on system Xc-cystine/glutamate transporter proteins. Imidazole ketone erastin has antitumor activity and induces glutathione depletion and l...		Ferroptosis
T77288	KKII5		Lipoxygenase
	KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons.		Lipoxygenase
T28978	Tirilazad mesylate	U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate	Antiviral
	Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral activity and neuroprotective activity.Tirilazad mesylate confines intracellular intramembranous foci, attenuates spinal c...		Antiviral
T4313	Tinoridine hydrochloride	Nonflamin,Y-3642 hydrochloride	COX , Glutathione Peroxidase
	Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxid...		COX , Glutathione Peroxidase
T25829	Mopidamol	RA233,RA 233,RA-233,Rapenton,OLX 102	PDE
	Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimental diabetes.		PDE
T35689	MTP 131 acetate		Others
	MTP 131 is a mitochondria-targeted peptide antioxidant.1,2It localizes to the mitochondria and reducestert-butyl hydroperoxide-induced lipid peroxidation and apoptosis in SH-SY5Y cells when used at concentrations ranging...		Others
T30863	CH 402	CH-402,CH402
	CH 402 inhibits lipid peroxidation.
T69462	Deulinoleic acid
	Deulinoleic acid is a lipid peroxidation inhibitor and antioxidant.
T70708	U 92032
	U 92032 is a T-channel antagonist and antioxidant that inhibits lipid peroxidation.
T69867	BN80933
	BN80933 is a dual inhibitor of lipid peroxidation and neuronal nitric oxide synthase; Neuroprotectant.
T35646	4-oxo-2-Nonenal	4-oxo-2-Nonenal,4-ONE
	4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid. [1] [2] It exhibits various biological activities such as cytotoxicity, ...
T24255	KB 5666	KB-5666,KB5666
	KB 5666, a quinazoline derivative, is a lipid peroxidation inhibitor. It protects the brain from both cellular and functional consequences of ischemia.
T19465	N6-Etheno 2'-deoxyadenosine		Others
	N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.		Others
T35963	MitoPerOx
	MitoPerOx is a ratiometric fluorescent probe that can be used to assess changes in lipid peroxidation within mitochondria. It is composed of a BODIPY fluorophore conjugated via a dienyl link to a triphenylphosphonium cat...
T23853	Carazostatin
	Carazostatin is an antioxidant, free radical scavenger, and potent lipid peroxidation inhibitor.
T69427	Peridinin
	Peridinin is an exceptionally potent and membrane-embedded inhibitor of bilayer lipid peroxidation.
T28082	Mollugogenol A
	Mollugogenol A is a Gammacerane from Mollugo pentaphylla. It is an antifungal saponin with spermatocidal activity. Mollugogenol A also involves sperm membrane damage by increased lipid peroxidation.
T28673	SB 209995	SB-209995,SB209995
	SB 209995, a potent antioxidant, inhibits oxygen-radical-mediated lipid peroxidation and cytotoxicity.
T70947	U-78517F
	U-78517F is a potent inhibitor of lipid peroxidation.
T35590	Graphislactone A
	Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislact...
T36002	4-hydroxy Hexenal	4-HHE,4-hydroxy Hexenal
	4-hydroxy Hexenal is a lipid peroxidation product derived from oxidized ω-3 fatty acids such as DHA. [1][2]
T22370	Mitoquinol mesylate		Others
	Mitoquinol, a ubiquinone derivative, specifically accumulates in mitochondria due to the covalent attachment of the cation triphenylphosphonium. Mitoquinol is an antioxidant, protecting mitochondria from oxidative damage...		Others
T36509	U-74389G	U-74389G,Methylated Tirilazad
	U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.[1],[2],[3],[4]
T39652	BODIPY 581/591 C11	BODIPY 581/591 C11
	C11-BODIPY581/591 is a fluorescent ratio-probe of lipid oxidation . C11-BODIPY581/591 is often used for indexing lipid peroxidation and antioxidant efficacy in model membrane systems and living cells. C11-BODIPY581/591 i...
T36175	AAPH
	AAPH is a water-soluble azo compound which is used extensively as a free radical generator, often in the study of lipid peroxidation and the characterization of antioxidants.[1],[2],[3],[4] Decomposition of AAPH produces...
T36168	8-iso-16-cyclohexyl-tetranor Prostaglandin E2	8-iso-16-cyclohexyl-tetranor Prostaglandin E2
	8-iso Prostaglandin E2 (8-iso PGE2) is one of several isoprostanes produced from polyunsaturated fatty acids during lipid peroxidation. 8-iso-16-cyclohexyl-tetranor PGE2 is a synthetic analog of 8-iso PGE2. There are no ...
T35462	(±)11-HETE
	(±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid . The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPL...
T36169	15-LOX-1 inhibitor 1
	9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1; IC50 = 0.19 μM).1 It decreases LPS- and IFN-γ-induced NF- B activity in RAW-Blue cells when used at concentrations of 0.2, 1, and 5 μM. 9c(i472) reduces LPS- and I...
T36164	8-iso Prostaglandin F3α	8-iso Prostaglandin F3α,8-epi PGF3α
	8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of h...
T35843	9(R)-HODE cholesteryl ester
	9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p...
T35853	9(S)-HODE cholesteryl ester
	9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p...
T35846	13(R)-HODE cholesteryl ester
	13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid ...
T78548	3-Hydroxyxanthone	3-Hydroxy-xanthen-9-one	Integrin
	3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein endothelial cells (HUVECs) and suppresses TNF-alpha-induced IC...		Integrin
T25943	Phenazoviridin
	Phenazoviridin is a newly discovered microbial free radical scavenger isolated from the culture medium of Streptomyces HR04. It is an anti-hypoxic compound with strong inhibitory activity against lipid peroxidation in ra...
T36558	(±)9-HETE
	(±)9-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPLC....
T68948	Detorubicin HCl
	Detorubicin is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair...
T68909	Detorubicin Free Base
	Detorubicin Free Base is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication ...
T81120	SP4f		PPAR
	SP4f, an activator of PPAR-γ, exhibits an EC50 value of 826 nM in HK-2 cells. In Swiss albino mice, it diminishes blood glucose levels and lipid peroxidation while enhancing glutathione levels and catalase activity [1].		PPAR
T36160	8-iso Prostaglandin E2	8-iso Prostaglandin E2
	8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with ...
T67870	DKI5	(E)-N'-benzylidenehydrazinecarbothiohydrazide	Lipoxygenase
	DKI5 ((E)-N'-benzylidenehydrazinecarbothiohydrazide) is a LOX-1 inhibitor with an IC50 value of 22.5 μM.DKI5 may have anti-inflammatory and antioxidant activities and has shown anti-lipid peroxidation activity in in vitr...		Lipoxygenase
T35993	Epitalon (acetate)
	Epitalon is a synthetic tetrapeptide with anti-aging properties.1,2,3,4 Dietary administration of epitalon (0.00001% w/w) reduces levels of lipid peroxidation products in aged D. melanogaster tissue homogenates.1 Epitalo...
T62347	MPO-IN-5
	MPO-IN-5 is a potent, irreversible inhibitor of MPO (myeloperoxidase). MPO-IN-5 inhibits MPO peroxidation (IC50: 0.22 μM) and hERG binding (IC50: 2.8 μM). 23000 M 1s 1.
T35962	MitoPBN
	MitoPBN is a mitochondria-targeted antioxidant. It accumulates in the mitochondria following the generation of a mitochondrial membrane potential by succinate, an effect that is blocked by addition of the mitochondrial m...
T36003	1(R)-(Trifluoromethyl)oleyl alcohol
	1(R)-(Trifluoromethyl)oleyl alcohol is an analog of oleic acid .1It inhibits ferroptosis induced by erastin in primary fibroblasts isolated from patients with Friedreich ataxia, a neuro- and cardiodegenerative disorder c...

Compounds

Lipid peroxidation inhibitor 1

Target: Adrenergic Receptor

Carvedilol phosphate hemihydrate

T0342

Synonym: Carvedilol phosphate,BM 14190 (phosphate hemihydrate)

Target: VEGFR, Others, Potassium Channel, LDL, Integrin, Gap Junction Protein, NADPH, Adrenergic Receptor, Autophagy

VK-28

T9956

Synonym:

Target: Mitochondrial Metabolism, Lipid

Imidazole ketone erastin

Synonym: U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate

Target: Antiviral

Tinoridine hydrochloride

T4313

Synonym: Nonflamin,Y-3642 hydrochloride

Target: COX, Glutathione Peroxidase

Mopidamol

T25829

Synonym: RA233,RA 233,RA-233,Rapenton,OLX 102

Synonym: CH-402,CH402

Synonym: 4-oxo-2-Nonenal,4-ONE

Target:

KB 5666

T24255

Synonym: KB-5666,KB5666

Target:

N6-Etheno 2'-deoxyadenosine

Synonym: SB-209995,SB209995

Synonym: 4-HHE,4-hydroxy Hexenal

Synonym: U-74389G,Methylated Tirilazad

Target:

BODIPY 581/591 C11

T39652

Synonym: BODIPY 581/591 C11

8-iso-16-cyclohexyl-tetranor Prostaglandin E2

T36168

Synonym: 8-iso-16-cyclohexyl-tetranor Prostaglandin E2

8-iso Prostaglandin F3α

T36164

Synonym: 8-iso Prostaglandin F3α,8-epi PGF3α

Target:

9(R)-HODE cholesteryl ester

T35843

Synonym:

Target:

9(S)-HODE cholesteryl ester

T35853

Synonym:

Target:

13(R)-HODE cholesteryl ester

Synonym: 3-Hydroxy-xanthen-9-one

Detorubicin Free Base

8-iso Prostaglandin E2

T36160

Synonym: 8-iso Prostaglandin E2

Target:

DKI5

T67870

Synonym: (E)-N'-benzylidenehydrazinecarbothiohydrazide

1(R)-(Trifluoromethyl)oleyl alcohol

T36003

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T19161	7α-Hydroxycholesterol		Others
	7α-Hydroxycholesterol is a cholesterol oxide formed by both enzymatic and non-enzymatic oxidation. It can be used as a biomarker for lipid peroxidation.		Others
T7982	3,6-Dihydroxyflavone		Others
	3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.		Others
TN2158	Robinetin	3,3',4',5',7-Pentahydroxyflavone	Anti-infection , HIV Protease , Antibacterial
	Robinetin (3,3',4',5',7-Pentahydroxyflavone) has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency.		Anti-infection , HIV Protease , Antibacterial
T0626	Uric Acid	2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate	Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase
	Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ...
T37710	5-Hydroxyoxindole		Reactive Oxygen Species
	5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activit...		Reactive Oxygen Species
TN4973	Sculponeatin O		Others
	Sculponeatin O may have protective effects on the lipid peroxidation-damaged live cells.		Others
TN1863	Licoisoflavone A	Phaseoluteone	MRP
	Licoisoflavone A (Phaseoluteone) is an MRP inhibitor and inhibits lipid peroxidation with an IC50 of 7.2 μM.		MRP
TN4972	Sculponeatin N		Others
	Sculponeatin N may have protective effects on the lipid peroxidation-damaged live cells.		Others
TN2374	Methyl Linolenate	Linolenic acid methyl ester	Others
	Methyl Linolenate (Linolenic acid methyl ester) is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids.		Others
TN3120	5-Hydroxy-7-acetoxy-8-methoxyflavone		Histone Demethylase , Antiviral
	5-Hydroxy-7-acetoxy-8-methoxyflavone is a flavonoid compound that inhibits lipid peroxidation and may have anti-influenza virus activity.		Histone Demethylase , Antiviral
T3S0289	Araloside X		Calcium Channel
	Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane perox...		Calcium Channel
TN2008	Okanin		NF-κB , TLR
	Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.		NF-κB , TLR
TN1962	Myricetin 3-O-galactoside	Myricetin 3-O-beta-D-galactopyranoside	NOS , Xanthine Oxidase
	Myricetin 3-O-galactoside (Myricetin 3-O-beta-D-galactopyranoside) can inhibit xanthine oxidase (xanthine oxidase; XO) activity, lipid peroxidation and scavenging free radicals. Myricetin 3-O-galactoside has many effects...		NOS , Xanthine Oxidase
TN2967	Pinobanksin 3-acetate	3-O-Acetylpinobanksin	Others , Antioxidant
	Pinobanksin 3-acetate (3-O-Acetylpinobanksin), a flavonoid derivative, is a strong antioxidant found in sunflowers and honey that inhibits LDL peroxidation.		Others , Antioxidant
T4241	Rubiadin	1,3-Dihydroxy-2-Methylanthracene-9,10-Dione	Free radical scavengers , PARP , Caspase
	Rubiadin (1,3-Dihydroxy-2-Methylanthracene-9,10-Dione) possesses potent antioxidant property, it can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner.		Free radical scavengers , PARP , Caspase
TN1644	Flavanomarein		Others
	Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...		Others
T19792	1,3,7-Trimethyluric acid		Others
	1,3,7-Trimethyluric acid is a purine alkaloid that occurs as a minor metabolite of caffeine in humans. As an antioxidant, it has shown an ability to scavenge hydroxyl radicals as well as protective potential against lipi...		Others
T0131	Cepharanthine	NSC-623442	Apoptosis , TNF , HIV Protease , Autophagy
	Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production.		Apoptosis , TNF , HIV Protease , Autophagy
T5S0636	Citric acid	Citro,Citretten	Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
	1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
T5S1285	(+)-(3R,8S)-Falcarindiol	Falcarindiol	Others
	1. (+)-(3R,8S)-Falcarindiol is a potential new anticancer agent that exerts its activity through inducing ER stress and apoptosis. 2. Falcarindiol induces immunosuppressive effects in vitro and in vivo and might be a nov...		Others
TN1725	Hederacolchiside E		Beta Amyloid , ROS
	Hederacolchiside E has antioxidant activity and shows neuroprotective effects in Alzheimer's disease (AD) models via modulating oxidative stress. Hederacolchiside E exhibits inhibition on lipid peroxidation of linoleic a...		Beta Amyloid , ROS
TN1624	Ethyl cinnamate		Calcium Channel , ROS , NO Synthase
	Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl...		Calcium Channel , ROS , NO Synthase
T4868	Gamma-Linolenic acid	gamolenic acid,γ-Linolenic acid	Endogenous Metabolite
	gamma-Linolenic acid (gamolenic acid), is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown γ-Linolenic Acid to have induced r...		Endogenous Metabolite
T2O2741	Thiamine monochloride	Thiamine chloride,Vitamin B1	Others , Antioxidant , Endogenous Metabolite , Antibacterial
	Thiamine monochloride (Vitamin B1) is an essential vitamin with erythropoietic, glucose-regulatory, antioxidant, and mood-regulatory properties.Thiamine monochloride inhibits lead-induced lipid peroxidation, thereby prev...
T3415	Secoisolariciresinol diglucoside	LGM2605	ROS
	Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglucoside (25 mg/kg b.w.) exerts the antihyperglycemic effect ...		ROS
TJS0315	4-Methyldaphnetin	7,8-Dihydroxy-4-methylcoumarin,DHMC	Apoptosis , Lipoxygenase
	4-Methyldaphnetin (DHMC) is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals, but may be pro-oxidant (enhancing generation of hydr...		Apoptosis , Lipoxygenase
T41242	Uric acid sodium		Reactive Oxygen Species
	Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric acid sodium, which removes reactive oxygen species (ROS) suc...		Reactive Oxygen Species
T5S1097	Neferine	(R)-1,2-Dimethoxyaporphine,(-)-Neferine	Apoptosis , NF-κB , Autophagy
	1. Neferine ((-)-Neferine) has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase the efficacy of DOX and to a...		Apoptosis , NF-κB , Autophagy
T2924	Phloretin	Dihydronaringenin,NSC 407292,RJC 02792	SGLT , transporter , Endogenous Metabolite
	Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leav...		SGLT , transporter , Endogenous Metabolite
T5S0106	Peimisine	Ebeiensine	RAAS , AChR
	1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...		RAAS , AChR
TN4406	Lamiide
	Lamiide has anti-inflammatory activity in carrageenin-induced paw edema test. It shows lipid peroxidation inhibition on rat-brain phospholipid peroxidation.
TN3069	4beta-Carboxy-19-nortotarol		NADPH-oxidase
	4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced by Fe(III)-ADP/ NADH, it inhibits linoleic acid autoxidation but not genera...		NADPH-oxidase
T3S2210	Lancerin		Others
	Lancerin, extracted from the root bark of Cudrania cochinchinensis, exhibits antioxidative activity against lipid peroxidation.		Others
TN1588	Dihydroisotanshinone I		ATPase , Potassium Channel , Calcium Channel
	Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scavenging activity and inhibition of lipid peroxidation.		ATPase , Potassium Channel , Calcium Channel
TN1896	Luteolin 5-O-glucoside	Luteollin 5-glucoside	Others
	Luteolin 5-O-α2-glucopyranoside has antioxidant activity, it can inhibit lipid peroxidation, and has DPPH radical-scavenging activity.		Others
TN4770	Phyllostadimer A		Others
	Phyllostadimer A can significantly inhibit liposomal lipid peroxidation.		Others
T74201	3′-Hydroxy-4′-O-methylglabridin
	3′-Hydroxy-4′-O-methylglabridin effectively prevents NADH-dependent peroxidation, exhibiting potent antioxidant properties [1].
T31102	Cryptopine	NSC32984,Kryptocavin,Cryptocavine,Kryptopine,Cryptopin
	Cryptopine in vivo disturbs the cellular defense system, so that it tips in the direction of autoxidative lipid peroxidation, producing cytotoxicity.
T13521	6"-O-Acetyldaidzin		Others
	6-O-Acetyldaidzin is an isoflavone glycoside isolated from soybeans. It significantly inhibits lipid peroxidation in rat liver microsome (IC50: 8.2 μM).		Others
T40368	4-Ethylresorcinol
	4-Ethylresorcinol, a derivative of resorcinol, functions as a tyrosinase substrate, possesses hypopigmentary effects, attenuates mRNA and protein expression of tyrosinase-related protein-2 (TRP-2), and exhibits antioxida...
T14062	6"-O-Acetylgenistin		Others
	6-O-Acetylgenistin is an isoflavone glycoside isolated from soybeans. 6-O-Acetylgenistin significantly inhibits lipid peroxidation in rat liver microsome with an IC50 of 10.6 μM[1][2].		Others
T74202	Hispaglabridin A
	Hispaglabridin A, an effective antioxidant, inhibits lipid peroxidation [1].
T81325	Quercetin 3-O-rutinoside-7-O-glucoside
	Quercetin 3-O-rutinoside-7-O-glucoside (compound 8), an antioxidant present in Hemerocallis fulva, exhibits potent inhibitory action against lipid peroxidation [1].
TN4388	Kielcorin		Antifection
	Kielcorin shows antibacterial activity against strain EMRSA-16. It also shows in vitro anti-inflammatory (respiratory burst) inhibiting activities using isolated human neutrophils (IC (50) = 965.21 ± 65.80 uM). trans-Kie...		Antifection
T82278	Glyurallin B
	Glyurallin B, a flavonoid derived from Glycyrrhiza inflata and Glycyrrhiza uralensis (licorice), exhibits ABTS+ radical scavenging activity and lipid peroxidation inhibition, with EC50 values of 11.9 ± 0.58 μM and 15.3 ±...
TN4877	Quercetin 3,4'-dimethyl ether		ERK , BCL , MAPK , Caspase , JNK
	Quercetin 3,4'-dimethyl ether shows anti-lipid peroxidation activity (IC 50 values of 0.3 uM), it also shows anti-inflammatory activity. Quercetin 3,4'-dimethyl ether could be useful in the development of novel anticance...		ERK , BCL , MAPK , Caspase , JNK
TN4212	Hirsutanonol		COX , Antifection
	Hirsutanonol is a secondary metabolite from the bark of Alnus glutinosa. Hirsutanonol has potent antioxidant and free radical scavenging activities and exhibits an inhibition effect on mitochondrial lipid peroxidation. H...		COX , Antifection
TN2876	3,4-Dihydroxy-2-methoxyxanthone		Antibacterial , Antifection
	3,4-Dihydroxy-2-methoxyxanthone shows antibacterial, and hepatoprotective activities, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell death in freshly isolated rat hepatocytes and is effective ...		Antibacterial , Antifection
T72594	Broussochalcone A
	Broussochalcone A, an antioxidant and Xanthine Oxidase inhibitor (IC 50 =2.21 μM), exhibits free radical scavenging activity. It prevents iron-induced lipid peroxidation and nitric oxide synthesis in lipopolysaccharide (...

Natural Products

7α-Hydroxycholesterol

Synonym: 3,3',4',5',7-Pentahydroxyflavone

Target: Anti-infection, HIV Protease, Antibacterial

Uric Acid

T0626

Synonym: 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate

Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase

5-Hydroxyoxindole

T37710

Synonym:

Target: Reactive Oxygen Species

Synonym: Phaseoluteone

Synonym: Linolenic acid methyl ester

Target: Others

5-Hydroxy-7-acetoxy-8-methoxyflavone

TN3120

Synonym:

Target: Histone Demethylase, Antiviral

Araloside X

T3S0289

Synonym:

Target: Calcium Channel

Myricetin 3-O-galactoside

TN1962

Synonym: Myricetin 3-O-beta-D-galactopyranoside

Target: NOS, Xanthine Oxidase

Pinobanksin 3-acetate

TN2967

Synonym: 3-O-Acetylpinobanksin

Target: Others, Antioxidant

Rubiadin

T4241

Synonym: 1,3-Dihydroxy-2-Methylanthracene-9,10-Dione

Target: Free radical scavengers, PARP, Caspase

1,3,7-Trimethyluric acid

Target: Apoptosis, TNF, HIV Protease, Autophagy

Citric acid

T5S0636

Synonym: Citro,Citretten

Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic

(+)-(3R,8S)-Falcarindiol

T5S1285

Synonym: Falcarindiol

Target: Beta Amyloid, ROS

Ethyl cinnamate

TN1624

Synonym:

Target: Calcium Channel, ROS, NO Synthase

gamma-Linolenic acid

T4868

Synonym: gamolenic acid,γ-Linolenic acid

Target: Endogenous Metabolite

Thiamine monochloride

T2O2741

Synonym: Thiamine chloride,Vitamin B1

Target: Others, Antioxidant, Endogenous Metabolite, Antibacterial

Secoisolariciresinol diglucoside

Synonym: 7,8-Dihydroxy-4-methylcoumarin,DHMC

Target: Apoptosis, Lipoxygenase

Uric acid sodium

T41242

Synonym:

Target: Reactive Oxygen Species

Neferine

T5S1097

Synonym: (R)-1,2-Dimethoxyaporphine,(-)-Neferine

Target: Apoptosis, NF-κB, Autophagy

Phloretin

T2924

Synonym: Dihydronaringenin,NSC 407292,RJC 02792

Target: SGLT, transporter, Endogenous Metabolite

4beta-Carboxy-19-nortotarol

TN3069

Synonym:

Target: NADPH-oxidase

Dihydroisotanshinone I

TN1588

Synonym:

Target: ATPase, Potassium Channel, Calcium Channel

Luteolin 5-O-glucoside

TN1896

Synonym: Luteollin 5-glucoside

3′-Hydroxy-4′-O-methylglabridin

Synonym: NSC32984,Kryptocavin,Cryptocavine,Kryptopine,Cryptopin

Quercetin 3-O-rutinoside-7-O-glucoside

Quercetin 3,4'-dimethyl ether

TN4877

Synonym:

Target: ERK, BCL, MAPK, Caspase, JNK

Hirsutanonol

TN4212

Synonym:

Target: COX, Antifection

3,4-Dihydroxy-2-methoxyxanthone

TN2876

Synonym:

Target: Antibacterial, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01588	ALDH7A1 Protein, Human, Recombinant (His)	Human	E. coli
	ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol...
TMPY-02582	Ferritin light chain Protein, Human, Recombinant (His)	Human	E. coli
	Ferritin, light polypeptide (FTL) is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light...
TMPY-02299	ALDH3A1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (...

ALDH7A1 Protein, Human, Recombinant (His)

TMPY-01588

Species: Human

Expression System: E. coli

Ferritin light chain Protein, Human, Recombinant (His)

TMPY-02582

Species: Human

Expression System: E. coli

ALDH3A1 Protein, Human, Recombinant (His)

TMPY-02299

Species: Human

Expression System: Baculovirus-Insect Cells

Cat No.	Product Name
L8700	Ferroptosis Compound Library		800 compounds
	A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；

Libraries

Ferroptosis Compound Library

L8700

Compounds: 800