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SARS-CoV-2-IN-14

SARS-CoV-2-IN-14
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Purity:99.3%
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SARS-CoV-2-IN-14

Catalog No. T60538Cas No. 22203-98-1
SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzyme. Oral administration of SARS-CoV-2-IN-14 can improve its bioavailability and half-life.
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Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$64In Stock
25 mg$98In Stock
50 mg$153In Stock
100 mg$229In Stock
1 mL x 10 mM (in DMSO)$47In Stock
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Product Introduction

Bioactivity
Description
SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzyme. Oral administration of SARS-CoV-2-IN-14 can improve its bioavailability and half-life.
Alias3',5-Dichlorosalicylanilide
Chemical Properties
Molecular Weight282.12
FormulaC13H9Cl2NO2
Cas No.22203-98-1
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 9 mg/mL (31.9 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5446 mL17.7230 mL35.4459 mL177.2295 mL
5 mM0.7089 mL3.5446 mL7.0892 mL35.4459 mL
10 mM0.3545 mL1.7723 mL3.5446 mL17.7230 mL
20 mM0.1772 mL0.8861 mL1.7723 mL8.8615 mL

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