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SLC13A5-IN-1
Catalog No. T12931Cas No. 2227548-95-8
SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $43 | In Stock | |
| 5 mg | $98 | In Stock | |
| 10 mg | $163 | In Stock | |
| 25 mg | $297 | In Stock | |
| 50 mg | $497 | In Stock | |
| 100 mg | $693 | In Stock | |
| 200 mg | $982 | In Stock | |
| 500 mg | $1,450 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $123 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells). |
| In vitro | In HepG2/14C-Citrate Uptake Assay,SLC13A5-IN-1 exhibits an IC50 of 0.022 μM . HepG2 cells endogenously express hSLC13A5 transporter which is responsible for the uptake of citrate into these cells. Uptake of 14C-citrate can be completely blocked by SLC13A5-IN-1 and the signal can be competed with unlabelled citrate.In recombinant hSLC3A5/14C-Citrate Uptake Assay, SLC13A5-IN-1 exhibits an IC50 of 0.056 μM . SLC13A5-IN-1 exhibits an IC50 of 100 μM in recombinant Human GlyT2/3H-Glycine Uptake Assay. The human embryonic kidney 293 cells are used that stably over-express the human GlyT2 receptor which is responsible for the uptake of glycine into these cells. Uptake of 3H-glycine can be completely blocked by SLC13A5-IN-1. |
| Molecular Weight | 461.79 |
| Formula | C19H19Cl3N2O3S |
| Cas No. | 2227548-95-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||
| Solubility Information | DMSO: 5 mg/ml (10.83 mM)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
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