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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0940 | Acesulfame Potassium | Others | |
Acesulfame potassium is a non-nutritive sweetener. | |||
TD0093 | Oil Red O | Others | |
The dry dye Oil red O is used for the preparation of a staining solution that can be used for the detection of lipids in histological cryo sections. | |||
T8337 | Nequinate | Xanthine Oxidase , Parasite | |
Nequinate is an anticoccidial agent, preventing coccidiosis . | |||
T9491 | Pyraclostrobin | Antibacterial , Antifungal | |
Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells. | |||
T8511 | TM38837 | Cannabinoid Receptor | |
TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes. | |||
T9609 | GRK5-IN-2 | GRK | |
GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. It regulates the expression and/or release of insulin and is useful for the metabolic disease research. | |||
T7092 | NADPH tetrasodium salt | Others , Ferroptosis , Endogenous Metabolite | |
NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of biological reactions. NADPH tetrasodium salt is also an end... | |||
T19857 | Glyphosate | Atila,Lancer,Folusen | Apoptosis , Autophagy |
Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans. | |||
T12931 | SLC13A5-IN-1 | Stearoyl-CoA Desaturase (SCD) | |
SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells). | |||
T12998 | SR10067 | Others , Autophagy | |
SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbα/β(IC50 of 160 and 170 nM for Rev-Erbβ and Rev-Erbα, respectively),has anxiolytic activity. | |||
T2216 | Entacapone | OR-611 | Transferase |
Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT). | |||
T21679 | 4'-bromo-Resveratrol | Sirtuin | |
4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3) | |||
T0413 | Cinromide | trans-3-Bromo-N-ethylcinnamamide | Others |
Cinromide (trans-3-Bromo-N-ethylcinnamamide) is used as a novel anticonvulsant agent. | |||
T7656 | Apelin-13 | ||
Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor angiotensin II protein J (APJ), with an EC50 value of 0.37 ... | |||
T7879 | TASP0415914 | Akt , PI3K | |
TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T | |||
T6574 | Lumiracoxib | Prexige,COX-189 | COX |
Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4. | |||
T10035 | 10,12-Tricosadiynoic acid | TDA,TCDA | Acyltransferase |
10,12-Tricosadiynoic acid is a highly selective and orally active inhibitor of acyl-CoA oxidase-1 (ACOX1). It can treat the high-fat diet- or obesity-induced metabolic diseases by improving mitochondrial lipid and ROS me... | |||
T0686 | Orlistat | Ro-18-0647,Tetrahydrolipstatin | Apoptosis , Others , Fatty Acid Synthase |
Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor. | |||
T5427 | GSK1940029 | SCD inhibitor 1 | Dehydrogenase , Stearoyl-CoA Desaturase (SCD) |
GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor. | |||
T19700 | IBC 293 | IBC293,IBC-293 | GPR |
IBC 293 is selective for GPR109B over niacin receptor GPR109A. IBC 293 is a highly selective agonist for GPR109B, a human orphan G-protein-coupled receptor expressed in adipocytes. | |||
T0773 | Febuxostat | TMX 67,TEI 6720 | ROS , Xanthine Oxidase |
Febuxostat (TEI 6720) is a xanthine oxidase Inhibitor. | |||
T14364 | AZ-Dyrk1B-33 | 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine | DYRK |
AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM. | |||
T9733 | PAL-4 | 1H-1,2,4-Triazol-5-amine, 3-[[(4-chlorophenyl)methyl]thio]-1-[(2,3-dihydro-5-benzofuranyl)sulfonyl]- | Others |
PAL-4 stimulates the activity of LYPLAL1, a poorly characterized serine hydrolase with complex genetic links to human metabolic traits. | |||
T22276 | Bis(maltolato)oxovanadium(IV) | BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV) | Phosphatase , Others |
Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent i... | |||
T13111 | Tegadifur | FD 1,40497S | Others |
Tegadifur is a drug of fluorine-containing and anti-metabolic. | |||
T19261 | D-Glucose-13C6 | D-(+)-Glucose-13C6,Glucose-13C6,Dextrose-13C6 | Endogenous Metabolite |
D-Glucose-13C6 (Dextrose-13C6) is an isotopic marker of D-Glucose, which can be used as a metabolic tracer for the study of metabolism-related diseases and metabolic processes of some substances in the body. | |||
T23209 | Qc1 | Qc 1 | Dehydrogenase |
Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases. | |||
T13260 | Gastrin/CCK antagonist 1 | cholecystokinin | |
Gastrin/CCK antagonist 1 is a potent gastrin/CCK antagonist for the study of metabolic system-related diseases. | |||
T11758 | KI696 isomer | Nrf2 | |
KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases. | |||
T0418 | Allylthiourea | N-Allylthiourea,Thiosinamine | MAO , Reactive Oxygen Species |
Allylthiourea (Thiosinamine), a metabolic inhibitor, specifically suppresses ammonia oxidation. | |||
T5411 | PDE10-IN-1 | SEP-0372814 | PDE |
PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders. | |||
T34385 | Ronacaleret HCl | SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689 | CaSR |
Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders. | |||
T31611 | Eldacimibe | WAY-ACA-147,UNII-4PBL76O2G8,ANA 147,ACA 147 | Acyltransferase |
Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, study of atherosclerosis and hypercholesterolemia. | |||
T11741 | KAN0438757 | Glucokinase , Autophagy | |
KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM. | |||
T39350 | Sebetralstat | KVD900 | Others |
Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases. | |||
T11978 | McN3716 | NSC359682,Methyl palmoxirate | Mitochondrial Metabolism , CPT |
McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor for the study of metabolic diseases. | |||
T19626 | LHW090-A7 | Neprilysin | |
LHW090-A7 is an neutral endopeptidase (NEP) inhibitor, and an enzyme responsible for the metabolic inactivation of enkephalins. | |||
T60908 | SARM1-IN-2 | Others | |
SARM1-IN-2 is a potent SARM1 inhibitor for the study of metabolic and neurological related diseases. | |||
T21457 | Carbazeran | UK-31557,UK31,557,UK-31,557,UK31557,UK 31557,UK 31,557 | PDE |
Carbazeran (UK-31,557) is an inhibitor of PDE2 and PDE3 and can be used for studies about metabolic diseases. Carbazeran shows inotropic and chronotropic effects in vivo(EC50 = 100 μM). | |||
T1470L | Fexofenadine hydrochloride | Histamine Receptor | |
Fexofenadine Hydrochloride is a carboxylated metabolic derivative of terfenadine and long-lasting selective histamine H1 receptor antagonist, with antihistaminic activity. | |||
T6112 | Doxercalciferol | TSA 840,Hectorol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2 | Others |
Doxercalciferol (TSA 840) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease. | |||
T77784 | WAY-297848 | Glucokinase | |
WAY-297848 is a novel glucokinase activator for the prevention or treatment of hyperglycemia, diabetes mellitus, obesity, dyslipidemia, and metabolic syndrome. | |||
T0068 | Fluphenazine dihydrochloride | Prolixin,Fluphenazine hydrochloride | Dopamine Receptor |
Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR; In studies, Fluphenazine can be used to probe the effects and metabolic process of this commonly used dopamine antagonist. | |||
T68132L | Quercetin-3'-o-phosphate TEA | Quercetin-3'-o-phosphate TEA(1111616-69-3 Free base),3'-quercetin phosphate TEA,Quercetin 3'-phosphate TEA | Adenosine Receptor |
Quercetin-3'-o-phosphate TEA (Quercetin 3'-phosphate TEA) is an adenosine A receptor antagonist that can be used to prevent and treat metabolic disorders. | |||
T11940 | Malic enzyme inhibitor ME1 | ME1 | Others |
Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity. | |||
T67579 | H-Glu(OMe)-OH | L-Glutamic acid 5-methyl ester | Amino Acids and Derivatives |
H-Glu(OMe)-OH is a glutamate derivative that is utilized in synthesizing various compounds and is related to immune and metabolic processes in the body. | |||
T74041 | GDP-L-fucose | Endogenous Metabolite | |
GDP-L-fucose is a nucleotide sugar widely found in fungi and plants and is involved in both the slave and secondary remedial metabolic pathways. | |||
T19663 | Triheptanoin | UX 007,IND106011,UX007,UX-007,IND 106011,IND-106011 | Others |
Triheptanoin (IND 106011) is a fatty acid metabolic modulator. It potentially for the treatment of fatty acid oxidation disorders and GLUT1. | |||
T60150 | (1S,2R)-Alicapistat | Cysteine Protease | |
(1S,2R)-Alicapistat ((1S,2R)-ABT-957) is a highly efficient, orally active compound that selectively inhibits human calpains 1 and 2, with promising implications for Alzheimer's disease (AD) therapy [1]. This compound ef... | |||
T7650 | Resazurin sodium | Resazurin sodium salt,Diazoresorcinol (sodium) | Antibacterial |
Resazurin sodium (Resazurin sodium salt) salt is a blue non-fluorescent dye,is widely used as a metabolic indicator for living cells |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4862 | Oxaloacetic acid | Endogenous Metabolite | |
Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate (the ionized form of oxaloacetic acid) ... | |||
T3836 | Eudesmin | MAPK , S6 Kinase | |
Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 m... | |||
T8392 | L(+)-Asparagine monohydrate | Endogenous Metabolite | |
L(+)-Asparagine monohydrate is a non-essential amino acid, participate in neurological and metabolic regulation of tissue cell function. | |||
T13795 | Nicotinamide riboside | Sirtuin | |
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. | |||
T4733 | Sucrose | D(+)-Sucrose,D-(+)-Saccharose | Others , Endogenous Metabolite |
Sucrose (D-(+)-Saccharose) is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. | |||
T0846 | L-Carnitine | L(-)-Carnitine,Levocarnitine | Endogenous Metabolite , Fatty Acid Synthase |
L-Carnitine (L(-)-Carnitine) is an amino acid derivative. L-Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utiliz... | |||
T2869 | Emodin | Frangula emodin | SARS-CoV , Casein Kinase , Autophagy |
Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways. | |||
T2S0271 | Voacamine | Voacanginine | Cannabinoid Receptor , P-gp |
Voacamine (Voacanginine) is an indole alkaloid. Voacamine exhibits potent cannabinoid CB1 receptor antagonistic activity. Voacamine also inhibits P-glycoprotein (P-gp) action in multidrug-resistant tumor cells.Voacangini... | |||
T19081 | 1,3-Dithiane | 1,3-Dithian,M-DITHIANE,1,3-Dithiacyclohexane | Anti-infection , Endogenous Metabolite , Antibacterial |
1,3-Dithiane (1,3-Dithian) is a protected formaldehyde anion equivalent that could serve as a useful labeled synthon. 1,3-Dithiane is also a sulfur-containing Maillard reaction products found in boiled beef extracts. | |||
T6220 | Nicotinamide riboside chloride | Sirtuin , Endogenous Metabolite | |
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+. | |||
T4S0554 | Theaflavine-3,3'-digallate | TFBG,theaflavin digallate | Others |
1. Theaflavine-3,3'-digallate (theaflavin digallate) and lactic acid together could reduce herpes simplex virus transmission. | |||
TN2121 | 3,5,7,3′,4′-Pentamethoxyflavone | Quercetin 3,5,7,3,4-pentamethyl ether | Others |
3,5,7,3′,4′-Pentamethoxyflavone (Quercetin 3,5,7,3,4-pentamethyl ether) is a natural product. It can induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation. | |||
T5588 | Cis,cis-Muconic acid | cis,cis-Muconate,cis,cis-2,4-Hexadienedioic acid | Others |
cis,cis-Muconic acid (cis,cis-2,4-Hexadienedioic acid) is a naturally-occurring organic acid. It is used in the manufacture of several widely-used consumer plastics. Its microbial production via extending the shikimate p... | |||
T1688 | Pregnanediol | 5Beta-Pregnane-3Alpha,20alpha-Diol,Pregnandiol | Estrogen/progestogen Receptor , Endogenous Metabolite |
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol(5Beta-Pregnane-3Alpha,20alpha-Diol) has two hydroxyl groups, at 3-alpha a... | |||
T3324 | Lycorine | Galanthidine,Narcissine,Amarylline,Belamarine,Licorine | Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase |
Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive. | |||
T3604 | Sodium dichloroacetate | Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA) | Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK |
Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion chann... | |||
T0529 | Dulcite | Galactitol,Dulcitol,Euonymit,NSC 1944,D-Galactitol,Melampyrit | Endogenous Metabolite |
Dulcite (D-Galactitol) is a sugar alcohol that is a metabolic breakdown product of galactose. | |||
TN7068 | Sinomenine N-oxide | Others | |
Sinomenine N-oxide is one of the major metabolites of the cyclic metabolic mechanism of Sinomenine. | |||
T7450 | 1-Phenylpropane-1,2-dione | 1-Phenyl-1,2-propanedione,Acetyl benzoyl | Others |
1-Phenylpropane-1,2-dione (Acetyl benzoyl) is a eukaryotic metabolite produced in plant metabolic reactions. | |||
T5788 | XYLOBIOSE | IL Receptor , TNF | |
XYLOBIOSE ia a natural product,and exhibited therapeutic potential for treating obesity which involved suppression of fat deposition and obesity-related metabolic disorders. | |||
T65172 | Flavin adenine dinucleotide | FAD | Endogenous Metabolite |
Flavin adenine dinucleotide (FAD) is a REDOX cofactor, a protein cogroup, involved in a variety of metabolic reactions. | |||
TQ0190 | D-Xylulose | Others , Endogenous Metabolite | |
D-Xylulose is converted from xylitol by the enzyme NAD+-linked xylitol dehydrogenase in the glucuronate pathway, the most important xylitol-handling metabolic pathway in mammals. | |||
TJS1159 | Chrysosplenetin | Chrysosptertin B | P450 , Ferroptosis , P-gp |
Chrysosplenetin is a metabolic inhibitor of artemisinin. | |||
T3S0289 | Araloside X | Calcium Channel | |
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane perox... | |||
T2799 | (20S)-Protopanaxadiol | 20-Epiprotopanaxadiol,20(S)-APPD | Apoptosis , Reactive Oxygen Species , P-gp |
(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin. | |||
T1192 | Protoporphyrin IX | PPIX | Others , Endogenous Metabolite |
Protoporphyrin IX (PPIX) is a tetrapyrrole containing 4 methyl, 2 propionic and 2 vinyl side chains that is a metabolic precursor for hemes, cytochrome c, and chlorophyll. | |||
TN3820 | Demethoxydeacetoxypseudolaric acid B | Others | |
Demethoxydeacetoxypseudolaric acid B's the metabolic reaction of TDA in vivo is mainly occurred in blood and contributes to be the hydrolysis of plasma esterase to ester bond, as well as the glucosylation reaction. | |||
TN3050 | 4'-Methoxyflavanone | Others | |
4'-Methoxyflavanone is a flavonoid isolated from natural Isaria fumosorosea KCH J2, which is used in the study of metabolic and cardiovascular diseases. | |||
TN1352 | N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide | (9Z,12Z)-N-(3-Methoxybenzyl)octadeca-9,12-dienamide,n-3-methoxybenzyl-9z-12z-octadecadienamide | Drug Metabolite |
N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide ((9Z,12Z)-N-(3-Methoxybenzyl)octadeca-9,12-dienamide) is a Macamide impurity that may be used in the study of metabolic diseases. | |||
T19538 | (R)-(-)-1,3-Butanediol | Endogenous Metabolite | |
(R)-(-)-1,3-Butanediol is a novel ketogenic ester that rapidly increases circulating concentrations of r- and s-ß-hydroxybutyric acid in healthy adults in a short period of time and can be used to study metabolic system-... | |||
T3O2784 | Vitamin B6 | Others | |
Vitamin B6 is a component of some coenzymes in human body, which is involved in a variety of metabolic reactions, especially related to amino acid metabolism.Clinical application of vitamin B6 in the prevention and treat... | |||
T4A2456 | Gamabufotalin | Gamabufagin | COX |
1. Gamabufotalin (Gamabufagin) , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect. | |||
T8073 | Disodium succinate | Sodium succinate | Others |
Disodium succinate (Sodium succinate) is the sodium salt form of succinate, which is an important metabolite at the cross-road of several metabolic pathways and involved in the formation and elimination of reactive oxyge... | |||
T10939L | L-Cystathionine | Cystathionine,ZINC1532680,L-(+)-Cystathionine,Cystathionine, L- | Apoptosis , Endogenous Metabolite |
L-Cystathionine (Cystathionine, L-) is a key nonprotein amino acid related to metabolic conditions of sulfur-containing amino acids. L-Cystathionine can be used in studies about cardiovascular protection. | |||
T2O2774 | L-Asparagine | alpha-aminosuccinamic acid,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine | Endogenous Metabolite |
L-Asparagine (Asparamide) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONIA by asparagine synthetase. | |||
T5268 | D-Arabitol | D-Lyxitol | Others , Endogenous Metabolite |
D-Arabitol (D-Lyxitol) is a polyol. Polyols are sugar alcohols linked to the pentose phosphate pathway (PPP). Polyols occur in body fluids. It is thought that D-arabitol is a metabolic end-product in humans. | |||
T5258 | Dodecanedioic acid diammonium salt | 1,10-Decanedicarboxylic acid diammonium salt | Others |
Dodecanedioic acid diammonium salt (1,10-Decanedicarboxylic acid diammonium salt) is a dicarboxylic acid which is water-soluble and involves in a metabolic pathway intermediate to those of lipids and carbohydrates. | |||
T6S1880 | Benzoylaconine | Pikraconitin,Isaconitine,Benzoylaconitine | Others |
Benzoylaconine (Isaconitine) is an alkaloid in the Chinese traditional medicine Radix Aconiti Lateralis Preparata (Fuzi). Benzoylaconine and aconitine can induce reproductive toxicity in BeWo Cell, the amino acid metabol... | |||
T3S0381 | Chrysophanol 8-O-glucoside | Serine Protease | |
Chrysophanol 8-O-glucoside and chrysophanol have mild cytotoxicity and anti-diabetic properties and can play metabolic roles in the insulin-stimulated glucose transport pathway | |||
TN1475 | Caulophyllogenin | Segetalic acid | IL Receptor , TNF , PPAR , Immunology/Inflammation related |
Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammatory cytokine secretion and can be used in studies about the... | |||
TMS2182 | Trans-Zeatinriboside | Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside | Others |
trans-Zeatinriboside (Ribosylzeatin) is the most active and ubiquitous form of the naturally occurring cytokinins that promote cell division, stimulate shoot proliferation, inhibit root formation, slow the aging process,... | |||
T19262 | D-Glucose 6-phosphate disodium salt | D-Glucose 6-phosphate disodium salt | Endogenous Metabolite |
D-Glucose 6-phosphate disodium salt is a compound widely present in biological systems. It is a molecule formed when glucose undergoes phosphorylation at the 6th carbon. This compound participates in various metabolic re... | |||
T1039 | Choline chloride | Biocolina,Biocoline,Hepacholine | AChR |
Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in li... | |||
T4238 | Glycocyamine | 2-Guanidinoacetic acid,Guanidoacetic acid | Others , Endogenous Metabolite |
Glycocyamine (2-Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird. Glycocyamine is an important marker for renal failure, kidney... | |||
T4852 | Trimyristin | Trimyristoylglycerol,Tritetradecanoin,Glyceryl trimyristate,1,2,3-Tritetradecanoylglycerol | Phosphatase , Endogenous Metabolite , AChE |
Trimyristin (Tritetradecanoin) is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging from yeast to humans. In humans, glyceryl trimyristate is i... | |||
T5253 | 3-Methyladipic acid | Others , Endogenous Metabolite | |
3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation, and so the w-oxidation pathway is the only metabo... | |||
TN6745 | PALATINOSE | TNP-470,Isomaltulose | Others |
PALATINOSE (TNP-470) is a natural occurring disaccharide composed of alpha-1,6-linked glucose and fructose。 PALATINOSE has a beneficial effect on liver metabolic functions and might therefore be a good substitute for suc... | |||
T6S1683 | Demethoxycurcumin | Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin | Apoptosis , Antioxidant , Antibacterial , Autophagy |
1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic e... | |||
T4734 | Suberic acid | Octanedioic acid,1,8-Octanedioic acid | Others , Endogenous Metabolite |
Suberic acid (1,8-Octanedioic acid) is present in the urine of patients with fatty acid oxidation disorders. A metabolic breakdown product derived from oleic acid. Elevated levels of this unstaruated dicarboxylic acid ar... | |||
TN1624 | Ethyl cinnamate | Calcium Channel , ROS , NO Synthase | |
Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl... | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06935 | FGF-21 Protein, Human, Recombinant | Human | E. coli |
Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes ... | |||
TMPK-00942 | DLK1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neu... | |||
TMPK-00639 | Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) | Rat | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00347 | Serum Albumin Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands i... | |||
TMPY-04753 | IRE1 Protein, Human, Recombinant (aa 465-977) | Human | Baculovirus-Insect Cells |
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ... | |||
TMPY-04413 | IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) | Human | Baculovirus-Insect Cells |
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ... | |||
TMPY-03101 | TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR... | |||
TMPY-01166 | TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His) | Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR... | |||
TMPY-01697 | TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR... | |||
TMPY-02279 | Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His) | Human | E. coli |
Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key en... | |||
TMPJ-00162 | IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc) | Human | Human Cells |
Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately ... | |||
TMPJ-00842 | FGF-2 Protein, Rat, Recombinant | Rat | E. coli |
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. ... | |||
TMPY-01369 | AGRP Protein, Human, Recombinant (His) | Human | HEK293 |
Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist ... | |||
TMPY-01460 | ABHD4 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain... | |||
TMPY-03363 | C-Reactive Protein Protein, Human, Recombinant | Human | HEK293 |
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reacti... | |||
TMPY-02047 | C-Reactive Protein Protein, Rat, Recombinant (His) | Rat | HEK293 |
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reacti... | |||
TMPY-00566 | CCL18 Protein, Human, Recombinant (His) | Human | Yeast |
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its... | |||
TMPY-05556 | Adiponectin Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other t... | |||
TMPY-02848 | Adiponectin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other t... | |||
TMPY-01278 | Apolipoprotein H/APOH Protein, Human, Recombinant (His) | Human | HEK293 |
Apolipoprotein H (APOH), also known as Beta-2-glycoprotein 1, Activated protein C-binding protein, B2GPI, and B2G1, is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipop... | |||
TMPH-02988 | UGPA Protein, Musa acuminata, Recombinant (His & Myc) | Musa acuminata | E. coli |
Plays a central role as a glucosyl donor in cellular metabolic pathways. | |||
TMPH-00016 | Ferredoxin Protein, Acetoanaerobium sticklandii, Recombinant (His & Myc) | Acetoanaerobium sticklandii | E. coli |
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | |||
TMPH-03464 | SUS1 Protein, S. cerevisiae, Recombinant (His & SUMO) | Saccharum officinarum | E. coli |
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. | |||
TMPY-02139 | FGF-21 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes ... | |||
TMPY-05794 | FGF-21 Protein, Hamster, Recombinant (His) | Hamster | HEK293 |
Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes ... | |||
TMPK-00369 | HGF Protein, Human, Recombinant (hFc) | Human | HEK293 |
Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different i... | |||
TMPY-01889 | FGF-21 Protein, Human, Recombinant (His) | Human | E. coli |
Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes ... | |||
TMPH-00722 | PykF Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the formation of pyruvate in the last step of glycolysis, it is irreversible under physiological conditions. The reaction is critical for the control of metabolic flux in the second part of glycolysis. | |||
TMPK-01274 | DLK1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neu... | |||
TMPK-00097 | FGF-21 Protein, Human, Recombinant (mFc & Avi) | Human | HEK293 |
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the document... | |||
TMPK-00098 | FGF-21 Protein, Human, Recombinant (mFc & Avi), Biotinylated | Human | HEK293 |
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the document... | |||
TMPK-00922 | DLK1 Protein, Human, Recombinant (aa 24-303, His) | Human | HEK293 |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neu... | |||
TMPK-00921 | DLK1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neu... | |||
TMPY-04554 | JNK1 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellula... | |||
TMPY-04764 | PCK2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. The levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabol... | |||
TMPJ-01072 | GALK2 Protein, Human, Recombinant (His) | Human | Human Cells |
GALK2 acts as a galactokinase when galactose is present at high concentrations. GALK2 may be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates. GALK2... | |||
TMPK-01150 | Beta Klotho Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, ... | |||
TMPK-01078 | Beta Klotho Protein, Human, Recombinant (His) | Human | HEK293 |
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, ... | |||
TMPH-02527 | ASS1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate f... | |||
TMPK-01326 | Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPJ-00586 | SULT1A2 Protein, Human, Recombinant (His) | Human | E. coli |
Sulfotransferase 1A2 (SULT1A2) is a member of the Sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. SULT1A2 is a cy... | |||
TMPK-00855 | Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00796 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPH-02509 | ANGPTL8 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storag... | |||
TMPH-02510 | ANGPTL8 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storag... | |||
TMPK-00801 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00802 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00684 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00804 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00803 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | ||
---|---|---|---|
L2560 | Metabolism Compound Library | 2350 compounds | |
A unique collection of 2350 metabolic pathway-related bioactive small molecule compounds for high-throughput, high-content screening. | |||
L2130 | Anti-Cancer Metabolism Compound Library | 1280 compounds | |
A unique collection of 1280 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS); | |||
L2550 | Glutamine Metabolism Compound Library | 580 compounds | |
A unique collection of 580 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... | |||
L5300 | Mitochondria-Targeted Compound Library | 830 compounds | |
A unique collection of 830 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; | |||
L2501 | Human Endogenous Metabolite Compound Library Plus | 1300 compounds | |
A unique collection of 1300 endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening. | |||
L1900 | Anti-Diabetic Compound Library | 690 compounds | |
A unique collection of 690 diabetes related compounds; | |||
L5100 | Fluorochemical Library | 583 compounds | |
A unique collection of 583 fluorochemicals that can be used for high through-put screening (HTS) and high content screening (HCS); | |||
L2540 | Gut Microbial Metabolite Library | 614 compounds | |
A unique collection of 614 gut microbial metabolites which can be used for HTS and HCS; | |||
L5500 | Toxic Compound Library | 277 compounds | |
A unique collection of 277 toxic substances for high throughput screening (HTS) and high content screening (HCS); | |||
L1510 | Nuclear Receptor Compound Library | 546 compounds | |
A unique collection of 546 nuclear receptor signaling targeted compounds for high throughput and high content screening; | |||
L9610 | Cyclic Peptide Library | 58 compounds | |
58 species of cyclic peptide molecules for high-throughput and high-content screening; | |||
L3200 | Autophagy Compound Library | 1248 compounds | |
A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L1600 | Kinase Inhibitor Library | 2720 compounds | |
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases; | |||
L7000 | Bioactive Lipid Compound Library | 385 compounds | |
A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, ... | |||
L1120 | AMPK-Targeted Compound Library | 80 compounds | |
80 well-chosen unique AMPK-targeted small molecules; | |||
L6600 | Anti-Gastroenteritis Natural Product Library | 223 compounds | |
A unique collection of 223 natural products related to gastroenteritis for high throughput screening (HTS) and high content screening (HCS); | |||
L2500 | Human Endogenous Metabolite Library | 508 compounds | |
A collection of 508 selected human endogenous metabolites for high throughput and high content screening. | |||
L2510 | Lipid Metabolism Compound Library | 496 compounds | |
A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). | |||
L2520 | Glycometabolism Compound Library | 708 compounds | |
708 glycometabolism-related comounds, can be used for HTS and HCT; | |||
L9600 | Peptide Compound Library | 800 compounds | |
800 peptides can be used in peptide drug development and signaling transduction and mechanism study; | |||
L7100 | Anti-Obesity Compound Library | 2286 compounds | |
A unique collection of 2286 anti-obesity compounds for high throughput and high content screening; | |||
L6400 | Marine Natural Product Library | 148 compounds | |
A unique collection of 148 marine natural products for high throughput screening (HTS) and high content screening (HCS); | |||
L7110 | Anti-Hypertension Compound Library | 719 compounds | |
719 hypertension-related small molecules for high-throughput and high-content screening. |