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VU 0364739 hydrochloride
🥰Excellent
Catalog No. T23512Cas No. 1244640-48-9
Alias VU 0364739 HCl
VU 0364739 hydrochloride (VU 0364739 HCl) is a selective and potent inhibitor of phospholipase D2 (PLD2) with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively.VU 0364739 hydrochloride exhibits potential anticancer activity and induces apoptosis. VU 0364739 hydrochloride has potential anticancer activity, induces apoptosis, and can be used in the study of cancer and metabolic-related diseases.
VU 0364739 hydrochloride
🥰Excellent
Purity: 99.36%
Catalog No. T23512Alias VU 0364739 HClCas No. 1244640-48-9
VU 0364739 hydrochloride (VU 0364739 HCl) is a selective and potent inhibitor of phospholipase D2 (PLD2) with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively.VU 0364739 hydrochloride exhibits potential anticancer activity and induces apoptosis. VU 0364739 hydrochloride has potential anticancer activity, induces apoptosis, and can be used in the study of cancer and metabolic-related diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $168 | In Stock | |
| 5 mg | $422 | In Stock | |
| 10 mg | $677 | In Stock | |
| 25 mg | $987 | In Stock | |
| 50 mg | $1,380 | In Stock | |
| 100 mg | $1,880 | In Stock |
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Purity:99.36%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | VU 0364739 hydrochloride (VU 0364739 HCl) is a selective and potent inhibitor of phospholipase D2 (PLD2) with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively.VU 0364739 hydrochloride exhibits potential anticancer activity and induces apoptosis. VU 0364739 hydrochloride has potential anticancer activity, induces apoptosis, and can be used in the study of cancer and metabolic-related diseases. |
| Targets&IC50 | PLD1:1500 nM, PLD2:20 nM |
| In vitro | MDA-MB-231 cells were cultured in the presence of VU 0364739 hydrochloride (1, 5, and 10 μM) for 24, 48, 72, and 96 hours, followed by determination of cell viability using the WST-1 cell proliferation reagent. The results indicate that VU 0364739 hydrochloride significantly reduces proliferation of MDA-MB-231 cells in a dose- and time-dependent manner[1]. |
| Alias | VU 0364739 HCl |
| Molecular Weight | 482.98 |
| Formula | C26H28ClFN4O2 |
| Cas No. | 1244640-48-9 |
| Smiles | Cl.O=C(NCCN1CCC2(C(=O)NCN2C=3C=CC=C(F)C3)CC1)C=4C=CC=5C=CC=CC5C4 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (20.70 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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