Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Su1498

🥰Excellent
Catalog No. T3980Cas No. 168835-82-3
Alias Tyrphostin SU 1498, AG 1498

Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.

Su1498

Su1498

🥰Excellent
Purity: 99.54%
Catalog No. T3980Alias Tyrphostin SU 1498, AG 1498Cas No. 168835-82-3
Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.
Pack SizePriceAvailabilityQuantity
1 mg$34In Stock
2 mg$47In Stock
5 mg$72In Stock
10 mg$122In Stock
25 mg$233In Stock
50 mg$346In Stock
100 mg$513In Stock
1 mL x 10 mM (in DMSO)$79In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "Su1498"

Select Batch
Purity:99.54%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.
Targets&IC50
VEGFR2:700 nM
AliasTyrphostin SU 1498, AG 1498
Chemical Properties
Molecular Weight390.52
FormulaC25H30N2O2
Cas No.168835-82-3
SmilesCC(C)c1cc(\C=C(/C#N)C(=O)NCCCc2ccccc2)cc(C(C)C)c1O
Relative Density.1.100 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 150 mg/mL (384.10 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5607 mL12.8034 mL25.6069 mL128.0344 mL
5 mM0.5121 mL2.5607 mL5.1214 mL25.6069 mL
10 mM0.2561 mL1.2803 mL2.5607 mL12.8034 mL
20 mM0.1280 mL0.6402 mL1.2803 mL6.4017 mL
50 mM0.0512 mL0.2561 mL0.5121 mL2.5607 mL
100 mM0.0256 mL0.1280 mL0.2561 mL1.2803 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Su1498 | purchase Su1498 | Su1498 cost | order Su1498 | Su1498 chemical structure | Su1498 formula | Su1498 molecular weight