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Su1498

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Purity:99.54%

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COA HNMR LCMS

Su1498

Catalog No. T3980Cas No. 168835-82-3

Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.

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Pack Size	Price	Availability
1 mg	$34	In Stock
2 mg	$47	In Stock
5 mg	$72	In Stock
10 mg	$122	In Stock
25 mg	$233	In Stock
50 mg	$346	In Stock
100 mg	$513	In Stock
1 mL x 10 mM (in DMSO)	$79	In Stock

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Product Introduction

Bioactivity

Description

Alias

Tyrphostin SU 1498, AG 1498

Chemical Properties

Molecular Weight	390.52
Formula	C25H30N2O2
Cas No.	168835-82-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 150 mg/mL (384.10 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5607 mL	12.8034 mL	25.6069 mL	128.0344 mL
5 mM	0.5121 mL	2.5607 mL	5.1214 mL	25.6069 mL
10 mM	0.2561 mL	1.2803 mL	2.5607 mL	12.8034 mL
20 mM	0.1280 mL	0.6402 mL	1.2803 mL	6.4017 mL
50 mM	0.0512 mL	0.2561 mL	0.5121 mL	2.5607 mL
100 mM	0.0256 mL	0.1280 mL	0.2561 mL	1.2803 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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