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Terodiline hydrochloride
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Catalog No. T13129Cas No. 7082-21-5
Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively).
Terodiline hydrochloride
😃Good
Catalog No. T13129Cas No. 7082-21-5
Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,220 | 1-2 weeks | |
| 50 mg | $1,590 | 1-2 weeks | |
| 100 mg | $2,430 | 1-2 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively). |
| In vivo | Terodiline treatment with 80 mg/kg; S.C. is equipotent in inhibiting intravesical bladder pressure and carbachol-induced salivary secretion with ID50 of 24 and 35 mg/kg, respectively, and in increasing pupil diameter with ED50 of 59 mg/kg. |
| Molecular Weight | 317.9 |
| Formula | C20H28ClN |
| Cas No. | 7082-21-5 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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