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Terodiline

TargetMol
Catalog No. T60536Cas No. 15793-40-5

Terodiline is a seconal amine with anticholinergic and calcium antagonistic properties that blocks the hERG current (IC50: 375 nM).Terodiline is cardiotoxic and has been used in the study of disorders caused by urethral muscle instability.

Terodiline

Terodiline

TargetMol
Purity: 99.41%
Catalog No. T60536Cas No. 15793-40-5
Terodiline is a seconal amine with anticholinergic and calcium antagonistic properties that blocks the hERG current (IC50: 375 nM).Terodiline is cardiotoxic and has been used in the study of disorders caused by urethral muscle instability.
Pack SizePriceAvailabilityQuantity
1 mg$293In Stock
5 mg$722In Stock
10 mg$987In Stock
25 mg$1,520In Stock
50 mg$1,980In Stock
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Purity:99.41%
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Product Introduction

Bioactivity
Description
Terodiline is a seconal amine with anticholinergic and calcium antagonistic properties that blocks the hERG current (IC50: 375 nM).Terodiline is cardiotoxic and has been used in the study of disorders caused by urethral muscle instability.
In vivo
In Hartley guinea pigs weighing 200-600 g (female or male), Terodiline (80 mg/kg; administered subcutaneously) yielded an ID50 of 24±6 mg/kg. Higher doses were lethal[1].
Chemical Properties
Molecular Weight281.44
FormulaC20H27N
Cas No.15793-40-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (355.3 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5532 mL17.7658 mL35.5316 mL177.6578 mL
5 mM0.7106 mL3.5532 mL7.1063 mL35.5316 mL
10 mM0.3553 mL1.7766 mL3.5532 mL17.7658 mL
20 mM0.1777 mL0.8883 mL1.7766 mL8.8829 mL
50 mM0.0711 mL0.3553 mL0.7106 mL3.5532 mL
100 mM0.0355 mL0.1777 mL0.3553 mL1.7766 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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